Spleen removal surgery and kidney function in cirrhosis patients
Part of Blood & lymphatic, Digestive system clinical trials.
This study tests whether removing an enlarged spleen through keyhole surgery can improve kidney function in people with cirrhosis and an overactive spleen. The trial follows patients for two years to see if the surgery helps protect the kidneys.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with cirrhosis of the liver.
- Your spleen is enlarged and is destroying blood cells too quickly (hypersplenism).
- You have never had bleeding from enlarged veins in your esophagus or stomach.
- You are between 18 and 80 years old.
- Your liver function is good enough (Child-Pugh class A or B).
- You do not have any kidney disease or have never had sudden kidney failure.
- You are willing to be followed for 24 months after the surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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