Spleen Removal Surgery and Kidney Health in Cirrhosis Patients
Part of Blood & lymphatic, Digestive system clinical trials.
This study tests whether removing an enlarged spleen during minimally invasive surgery can help protect kidney function in people with cirrhosis (liver scarring). Researchers will follow participants for 2 years to see how the surgery affects their kidneys.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Confirmed diagnosis of liver cirrhosis (scarring) confirmed by blood tests, imaging, or physical exam
- Enlarged spleen with low blood cell counts (hypersplenism)
- Never had bleeding from enlarged veins in the esophagus or stomach
- Age between 18 and 80 years old
- Liver function rated as Child-Pugh Class A or B (not the most severe)
- No previous kidney disease or acute kidney injury, and able to complete 24 months of follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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