Balloon procedure in pregnancy for severe diaphragmatic hernia
Part of Genetic & congenital clinical trials.
This trial studies a prenatal procedure called FETO, where a small balloon is placed in the fetal windpipe to help lung growth in babies with a severe diaphragmatic hernia. It may improve newborn outcomes by preparing the lungs before birth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be pregnant, age 18 or older, with one baby (singleton pregnancy)
- Agree to sign consent and follow all study visits and procedures for the pregnancy
- Have a clear genetic test (normal microarray/karyotype); if late in pregnancy, some other accepted tests may work
- The baby must have diaphragmatic hernia with very severe underdeveloped lungs (based on LHR and liver position) and a fetal heart ultrasound with no major heart defects
- Be able to travel and stay near NewYork-Presbyterian/Columbia (within 30 minutes) and attend frequent follow-ups
- You must not have certain medical risks (for example, specific allergies, preterm-cervix issues, placenta problems, some infections, or not being safe for the procedure)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a procedure to place a balloon in the windpipe of a fetus with a severe diaphragm defect before birth. The balloon may help the lungs grow, and is removed before delivery.
This trial tests if placing a temporary balloon in the baby's windpipe before birth can improve survival for babies with a severe form of a diaphragmatic hernia. It is for pregnant women carrying a single baby with a left-sided hernia that is more severe or a right-sided hernia, and whose liver is up in the chest.
This trial studies whether placing a small balloon in the fetus’s airway during pregnancy (a procedure called FETO) can improve lung development and outcomes for babies with severe left congenital diaphragmatic hernia. You may be considered if the condition is isolated, very severe, and you can meet specific timing and follow-up requirements.
This trial studies a fetal procedure called FETO that places a small balloon in the baby’s windpipe to help the lungs grow in severe congenital diaphragmatic hernia (CDH). It may help babies with very small lung development after birth, but you must meet specific pregnancy, genetic, and safety requirements.
This study tests a fetal surgery (fetoscopic tracheal balloon placement) to help lungs grow in babies with a severe hole in the diaphragm. It focuses on pregnancies where the liver is also in the chest and lung size is very small.
This trial tests a special pregnancy procedure called FETO to help babies born with severe congenital diaphragm hernia (CDH) breathe better after birth. It may help by improving lung growth, but it requires close follow-up at a Chicago fetal center.
Hear when a new Diaphragmatic Hernia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.