Fetoscopic tracheal occlusion for severe diaphragmatic hernia
Part of Genetic & congenital clinical trials.
This trial tests a fetal surgery procedure for severe congenital diaphragmatic hernia (CDH), where a doctor temporarily blocks the baby's windpipe to help the lungs grow. It aims to improve survival chances for pregnancies with this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old and pregnant with one baby.
- Have a baby diagnosed with severe left or right CDH with poor lung growth, confirmed by ultrasound.
- Be between 18 and 29 weeks pregnant when the diagnosis is confirmed, and between 27 and 29 weeks when the surgery is done.
- Be willing to stay within 30 minutes of the hospital (NYU Langone Health) from the time of surgery until the balloon is removed.
- Have a support person available to stay with you near the hospital during the pregnancy.
- Agree to avoid exercise, intercourse, and work during the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a prenatal procedure called FETO, where a small balloon is placed in the fetal windpipe to help lung growth in babies with a severe diaphragmatic hernia. It may improve newborn outcomes by preparing the lungs before birth.
This trial tests if placing a temporary balloon in the baby's windpipe before birth can improve survival for babies with a severe form of a diaphragmatic hernia. It is for pregnant women carrying a single baby with a left-sided hernia that is more severe or a right-sided hernia, and whose liver is up in the chest.
This trial studies a fetal procedure (FETO) that temporarily blocks the baby’s windpipe to help lung growth before birth. It may help babies with severe lung underdevelopment from an isolated left diaphragmatic hernia (CDH) who meet specific pregnancy and fetal criteria.
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
This trial tests a procedure called FETO (fetoscopic endoluminal tracheal occlusion) performed during pregnancy to help babies with congenital diaphragmatic hernia—a birth defect where part of the diaphragm (breathing muscle) has a hole and organs from the belly move into the chest. The procedure temporarily blocks the baby's windpipe to help the lungs grow bigger before birth.
This trial studies a fetal procedure called FETO that places a small balloon in the baby’s windpipe to help the lungs grow in severe congenital diaphragmatic hernia (CDH). It may help babies with very small lung development after birth, but you must meet specific pregnancy, genetic, and safety requirements.
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