Adaptive proton therapy for cervical cancer with chemo
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial tests whether an “adaptive” type of radiation planning using proton therapy and MRI-guided brachytherapy can improve treatment for people with cervical cancer. It aims to deliver curative treatment more precisely while still combining it with chemotherapy (cisplatin) when appropriate.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed cervical cancer (common types) and you are planned for curative treatment with chemotherapy plus radiation and then image-guided brachytherapy
- Your radiation plan includes specific lymph node areas: either the common iliac region (5–8 spots/levels) or common iliac plus para-aortic regions (7–10 spots/levels)
- Your scans (CT or PET-CT) show no cancer spread beyond the para-aortic lymph node chain
- You are at least 18 years old and well enough to do treatment (WHO 0–1)
- Your kidneys, bone marrow, and blood counts are strong enough for weekly chemo (cisplatin, or carboplatin if needed)
- You can travel for treatment and follow-up, and you can have MRI for the study (no MRI contraindications)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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