Clin2
NCT05406947Possibly a fitNot yet recruiting

Refining risk classification for medulloblastoma using tumor genetics

Medulloblastoma, Childhood

Part of Cancer clinical trials.

This study looks at the DNA of medulloblastoma (a common childhood brain tumor) to create a better way of classifying the tumor's risk. By understanding the tumor's specific genetic features, doctors hope to tailor treatment more accurately and improve outcomes for children.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
350 people
Ages
6 months to 18 years
Study type
Observational

Who can take part

  • Child is between 6 months and 18 years old.
  • Has a confirmed diagnosis of medulloblastoma.
  • Has not received prior treatment for the tumor before surgery.
  • Had an MRI with contrast of the brain and spine.
  • Is generally in good health and able to follow up for a long time.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05057702Recruiting
Personalized surgery-focused treatment plan for relapsed brain cancer

This study tests a personalized treatment plan for children and young adults whose medulloblastoma or ependymoma has come back. It aims to guide doctors using new tissue from surgery or biopsy after earlier treatments are fully finished.

Los Angeles, California
NCT06959979Recruiting· Early Phase 1
Studying New Treatments for Medulloblastoma

This trial is studying the genetic details of medulloblastoma tumors in children to find new, targeted treatments. If your child had surgery for medulloblastoma at our pediatric center, their tumor tissue may help us learn more.

Roma, ROMA
NCT06942039Recruiting· Early Phase 1
Study of two drugs for young children with aggressive brain tumors

This trial tests a combination of chemotherapy drugs (topotecan given into the spine plus maintenance chemo) for children under 6 with high-risk embryonal brain tumors. The goal is to see if this approach can improve outcomes after initial treatment.

Calgary, Alberta
NCT05672043Recruiting
Study genetic risks in children with malignant brain tumors

This study looks at genetic (DNA/molecular) features of malignant brain tumors in children. It may help doctors better understand tumor risk patterns and guide future treatment planning.

Beijing, Beijing Municipality
NCT05535166Recruiting· Phase 2
Risk- and lab-guided treatment for young children with medulloblastoma

This Phase 2 trial tests how doctors choose treatment for infants and young children with newly diagnosed medulloblastoma, based on MRI/CSF staging and lab testing of the tumor. It may help by matching therapy intensity to the child’s specific risk level and tumor type.

Palo Alto, California
NCT06814353Enrolling by invitation
Studying where medulloblastoma starts in the brain

This trial observes where medulloblastoma tumors first appear and how they grow during surgery. It helps doctors better understand these rare childhood and adult brain tumors.

Vienna, State of Vienna

Hear when a new Medulloblastoma, Childhood trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.