Clin2
NCT05427695Possibly a fitRecruiting

Probiotic rinse to treat chronic sinus inflammation

Chronic Rhinosinusitis (Diagnosis)

Treatments studied

Part of Ear, nose & throat clinical trials.

This Phase 2 study tests whether washing your sinuses with a probiotic solution can improve chronic sinusitis symptoms and inflammation. It’s for adults with chronic sinus symptoms that have flared, especially if you’ve had sinus surgery in the past.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are age 18 or older.
  • You have chronic sinusitis with a recent flare-up—worse nasal blockage, discharge, facial pressure/pain, or reduced sense of smell—plus endoscopy findings showing inflammation and/or infection.
  • You had functional endoscopic sinus surgery more than 12 months ago, and your treating clinician believes your sinuses are suitable for this trial.
  • You are willing and able to follow the study plan, including filling out questionnaires during the study.
  • You agree to sign informed consent after learning the purpose and procedures of the study.
  • You are not currently using (or won’t stop) topical antibiotic sinus rinses, and you are not pregnant or breastfeeding (if applicable).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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