Reducing stress before ovarian cancer surgery with two medicines
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study tests whether giving two commonly used medicines before surgery—one that can lower stress on the body (a beta-blocker) and one that reduces inflammation (a COX-2 inhibitor)—can improve outcomes compared with standard care. It’s for people with advanced ovarian, fallopian tube, or primary peritoneal cancer who are having open surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced (stage II–IV) ovarian, fallopian tube, or primary peritoneal cancer
- You are scheduled for open abdominal surgery (exploratory laparotomy) and either PDS or IDS
- Your surgery is at least 10 days away, so you can start the study medicines 7 days before surgery
- You’re age 18 or older and able to consent and follow the study plan
- You have no long-term use of beta-blockers or COX inhibitors
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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