Treatment
Propranolol clinical trials
We’re tracking 42 recruiting studies that include Propranolol, each written for real people, not researchers, below.
Recruiting studies
- NCT07352228Enrolling by invitationPhase 4
Comparing carvedilol and propranolol to prevent variceal rebleeding
This trial tests whether carvedilol or propranolol works better to prevent another bleeding episode from enlarged veins in the stomach or esophagus (varices) after they have been treated with endoscopy. If you have cirrhosis and had a variceal bleed 6 to 30 days ago, this study may help find the most effective medicine for you.
Xi'anAges 18–75 - NCT05979818RecruitingPhase 1
Propranolol plus immunotherapy and chemo for advanced lung cancer
This trial tests adding a beta-blocker (propranolol) to a combination of immunotherapy (sintilimab) and standard chemotherapy for people with advanced non-small cell lung cancer that hasn't been treated before. The goal is to see if this new triple treatment helps shrink tumors better than chemo-immunotherapy alone.
Changsha, HunanAges 18–75 - NCT05651594RecruitingPhase 2
Propranolol with pembrolizumab and chemotherapy for esophageal cancer
This trial tests whether adding propranolol (a common blood-pressure/heart medicine) can improve outcomes when used with pembrolizumab plus standard chemotherapy. It is for people with advanced esophageal or gastroesophageal junction adenocarcinoma that cannot be removed with surgery.
Buffalo, New YorkAges 18 years+ - NCT04682158RecruitingPhase 2
Propranolol added to standard chemoradiation for esophageal cancer
This trial studies whether adding propranolol (a common blood-pressure/heart medication) to standard chemotherapy and radiation can improve outcomes for people with esophageal adenocarcinoma. You would start propranolol around the time of treatment, with careful heart monitoring and study follow-up.
Buffalo, New YorkAges 18 years+ - NCT07271485RecruitingEarly Phase 1
Propranolol for misophonia: a pilot study
This trial tests if a blood pressure medication called propranolol can reduce the intense anger or anxiety some people feel in response to everyday sounds (like chewing or breathing). If you have misophonia and meet the study’s health and safety criteria, you may be able to join and receive the medication under medical supervision at a clinic in Littleton, Colorado.
Littleton, ColoradoAges 18–65 - NCT07743255Enrolling by invitation
Preventing migraines in children with melatonin and propranolol
This study tests whether two common medicines, melatonin and propranolol, can help prevent migraines in children. If your child has frequent, disabling migraines, this treatment might reduce how often they occur and improve daily life.
Multan, Punjab ProvinceAges 5–15 - NCT06798363RecruitingPhase 2/Phase 3
Testing different doses of propranolol for ulcerated hemangioma in children.
This trial tests different starting doses of oral propranolol to see which works best and is safest for treating infantile hemangiomas that have ulcers (sores). It may help your child heal faster.
Chengdu, SichuanAges 1 month–4 years - NCT03083431RecruitingPhase 2
Oral propranolol to prevent early retinopathy in preemies
This trial tests whether giving propranolol by mouth to certain very premature babies with early eye changes can stop retinopathy of prematurity from getting worse. It may help reduce the need for eye treatments later on.
Tübingen, Baden-WurttembergAges 1 month–3 months - NCT04186286RecruitingPhase 2
Testing propranolol vs ivabradine for POTS symptoms
This study compares two heart-rate medicines—propranolol and ivabradine—to see which better improves symptoms in people with POTS. It uses a “crossover” design, meaning you may try one medicine and then switch to the other.
Calgary, AlbertaAges 18–60 - NCT04985344RecruitingPhase 3
Propranolol to treat PTSD symptoms in children using memory reactivation
This trial studies whether propranolol (a heart-related medicine) can help children with post-traumatic stress disorder (PTSD) after a special memory-activation session. The goal is to reduce PTSD symptoms compared with the comparison condition.
ToulouseAges 7–12 - NCT05424016Recruiting
Propranolol for brain blood-vessel tumors in VHL
This trial studies whether propranolol, a beta-blocker medicine, can help people with VHL who have non-urgent hemangioblastomas in the brain/spinal cord. It aims to see if the medication is safe and beneficial without needing immediate surgery.
Le Kremlin-BicêtreAges 18 years+ - NCT05451043RecruitingPhase 2
Durvalumab and tremelimumab plus chemotherapy with propranolol
This Phase 2 study tests whether adding propranolol to durvalumab and tremelimumab along with chemotherapy can help control advanced pancreatic cancer, liver cancer, or bile duct cancer. It aims to shrink tumors and help people live longer or feel better when the cancer can’t be cured with surgery or local treatment.
Edmonton, AlbertaAges 18 years+ - NCT05587361RecruitingPhase 4
Nicotine cue study using propranolol to study craving
This study tests whether a beta-blocking medicine (propranolol) and nicotine patches change how strongly your brain responds to smoking cues. It may help researchers understand what drives cigarette cravings and how to reduce them.
Tulsa, OklahomaAges 21–60 - NCT05741164RecruitingPhase 2
Propranolol plus pembrolizumab for hard-to-treat breast cancer
This Phase 2 trial studies whether adding propranolol to pembrolizumab can “re-sensitize” tumors and slow cancer in triple-negative breast cancer that no longer responds to checkpoint immunotherapy. It may help some people whose cancer has grown despite prior pembrolizumab and chemotherapy.
Atlanta, GeorgiaAges 18 years+ - NCT05853627RecruitingPhase 4
Propranolol versus standard therapy for trauma imagery reactions
This study tests whether propranolol (a beta-blocker) changed alongside a standard approach can reduce how strongly your body reacts during traumatic imagery. It’s meant for adults who have had a traumatic event and may help lessen fear and stress responses tied to those memories.
Charlestown, MassachusettsAges 18–65 - NCT05961761RecruitingPhase 2
Testing propranolol plus pembrolizumab for advanced sarcoma
This Phase 2 trial tests whether combining propranolol (a blood-pressure/heart medicine) with pembrolizumab (an immune therapy) can help people with advanced angiosarcoma or undifferentiated pleomorphic sarcoma that has progressed after first-line chemotherapy. It aims to slow tumor growth and improve outcomes while also studying tumor markers from your biopsy tissue.
AarhusAges 18 years+ - NCT05968690RecruitingPhase 1
Testing naltrexone and propranolol with melanoma immunotherapy
This Phase 1 study tests whether adding naltrexone and propranolol to standard immunotherapy (ipilimumab plus nivolumab) can improve outcomes for people with advanced melanoma. It also aims to better understand safety and how the combination works in the body.
New Brunswick, New JerseyAges 18 years+ - NCT06066710RecruitingEarly Phase 1
Propranolol for Primary Progressive Aphasia
This trial tests whether the drug propranolol, often used for high blood pressure, can help people with primary progressive aphasia (a condition that slowly affects language skills). You would take the drug and have MRI brain scans to see if it slows language decline.
Columbia, MissouriAges 50 years+ - NCT06145074RecruitingPhase 2
Testing propranolol before surgery for pancreatic cancer
This trial tests if taking propranolol (a blood pressure medication) before surgery helps treat pancreatic cancer that can be removed. It aims to see if the drug is safe and works well.
CopenhagenAges 18 years+ - NCT06445166RecruitingPhase 2
Propranolol for Kaposi Sarcoma in adults
This trial tests if the blood pressure medication propranolol can treat Kaposi Sarcoma (a type of skin cancer) in adults. You may be able to join if you have at least 7 measurable skin lesions and are otherwise healthy enough to take an oral pill.
St Louis, MissouriAges 18 years+ - NCT06485726RecruitingPhase 4
Comparing valproate and propranolol for migraine prevention
This study compares two common migraine prevention medications—valproate (a seizure medicine) and propranolol (a blood pressure medicine)—to see which works better for people with migraines who have never tried prevention before. You may benefit if you experience migraines and are looking for a safe first-line preventive option.
Kafr ash ShaykhAges 18–75 - NCT06775080RecruitingPhase 2
Testing propranolol before and after surgery for stomach or colon cancer
This trial tests if taking a medicine called propranolol around the time of surgery can improve outcomes for people with stomach or colon cancer that can be removed with an operation. Propranolol is a type of drug that blocks certain stress signals in the body and may help with recovery.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06839144RecruitingPhase 2
Medications before surgery to slow ovarian cancer growth
This trial tests whether giving two common medications before and after surgery can slow the growth of ovarian cancer. The medications may help reduce stress signals that could make cancer spread faster during surgery.
Ramat GanAges 20–85 - NCT06982183RecruitingPhase 4
Propranolol and hydrocortisone effects on military performance
This trial studies how two medications—propranolol (a beta blocker often used for anxiety) and hydrocortisone (a steroid)—affect performance on military tasks. It aims to understand if these drugs help or hinder how soldiers perform under stress.
Silver Spring, MarylandAges 18–40
What Propranolol is being studied for
Conditions with recruiting Propranolol studies.
Common questions
- Are there clinical trials studying Propranolol?
- Yes. Clin2 currently lists 42 recruiting studies that include Propranolol, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Propranolol trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Propranolol an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Propranolol or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.