Clin2
NCT05434195Possibly a fitRecruiting

Study folate in pregnancies with high blood pressure

Pre-EclampsiaPregnancy Induced HypertensionPregnancy Related

Part of Heart & circulation, Women’s health & pregnancy clinical trials.

This study looks at how a vitamin called tetrahydrofolate may affect pregnancies with preeclampsia or increased risk of high blood pressure. Participants may receive the supplement to help researchers understand key biology and potential benefits or harms.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
128 people
Ages
18 years to 45 years
Study type
Interventional

Who can take part

  • You are pregnant and either have preeclampsia (under 34 weeks) or are normotensive with low risk
  • If you have preeclampsia: diagnosis was within the past 48 hours and no delivery is planned in the next week
  • You get antenatal care at John Radcliffe Hospital
  • You’re age 18 to 45, and you can agree to take part (informed consent)
  • You can’t take folate supplements above 400 mcg in the third trimester, and your B12 must not be low
  • You must not have certain heart, kidney, medication, or pregnancy/fetal conditions

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07072052Not yet recruiting
Early pregnancy study for placental health at Oxford

This study looks at how the body supports pregnancy in the early weeks and whether problems with that support can lead to complications. By tracking pregnancies from the start, researchers hope to find ways to predict and prevent issues like poor placental function.

Oxford
NCT06069856Not yet recruiting· Phase 3
Prenatal vitamin preference study

This study compares two types of prenatal supplements: a multi-vitamin/mineral supplement (includes extra nutrients) versus the standard iron and folic acid. It aims to see which one women prefer and how well they accept it during early pregnancy.

NCT05746793Recruiting
IVF pregnancy study to prevent pre-eclampsia in high-risk women

This trial studies ways to lower the risk of pre-eclampsia (dangerous high blood pressure in pregnancy) in women who are having a first pregnancy through IVF/ICSI or who have PCOS. It’s aimed at people considered higher risk for pre-eclampsia.

Brussels
NCT06641245Not yet recruiting
Folic acid before pregnancy for preventing birth defects

This study compares different doses of folic acid (a B vitamin important for preventing birth defects) for women who are planning to become pregnant. It aims to find the most effective dose to support a healthy pregnancy.

NCT06700044Recruiting
Probiotics for high-risk pregnancy

This study tests whether taking a probiotic supplement during pregnancy can help prevent complications in women at risk for preeclampsia. You would take a daily probiotic or placebo pill from about 20 weeks until delivery.

Lund
NCT05676476Recruiting
Tested extra blood-pressure control to extend pregnancy in preeclampsia

This trial studies whether using specific blood-pressure medicines can help people with non-severe preeclampsia stay pregnant longer. It aims to improve outcomes by treating blood pressure early while monitoring you and the baby closely.

Birmingham, Alabama

Hear when a new Pre-Eclampsia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.