Clin2
NCT05440422Possibly a fitRecruiting

Anifrolumab for heart health in lupus patients

Systemic Lupus ErythematosusCardiovascular DiseasePremature Atherosclerosis

Treatments studied

Part of Heart & circulation, Immune system & allergy, Skin clinical trials.

This study tests whether anifrolumab, a drug that targets the immune system, can improve markers of blood vessel health in people with lupus. It may help reduce the risk of heart problems associated with lupus.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
45 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old.
  • You have been diagnosed with lupus (SLE).
  • You are on a stable dose of prednisone (10 mg/day or less) for at least 2 weeks before the study starts.
  • You have abnormal blood vessel stiffness or inflammation, as measured by a special test (CAVI, PWV, or PET scan).
  • You are willing to use effective contraception if you or your partner can become pregnant.
  • You have been vaccinated against COVID-19 and shingles (varicella zoster).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07430306Recruiting· Phase 3
Study of anifrolumab for lupus patients not yet on strong treatments

This trial tests if a new drug called anifrolumab can help treat lupus in people who haven't taken strong medications like biologics or immunosuppressants before. It looks at overall disease activity and the chance to reduce steroid use.

Anniston, Alabama
NCT07000110Recruiting
Anifrolumab and risk study for lupus patients

This study looks at potential risks of the lupus medication anifrolumab in people with moderate to severe SLE. It focuses on serious infections and malignancies to see how safe the treatment is.

Copenhagen
NCT07688980Not yet recruiting· Phase 1
Anifrolumab for active lupus: how it works in the body

This study tests an experimental drug called anifrolumab, which is given as an injection or infusion, to see how it works in people with active lupus. It may help reduce lupus symptoms by targeting the immune system.

NCT07215754Recruiting
Real-world study of anifrolumab for active lupus

This study tracks how well anifrolumab works and how safe it is for people with active lupus. It's a real-world look at the drug's effects, so no additional treatments or tests are required beyond what your doctor already prescribes.

Pisa
NCT06784076Not yet recruiting
Study of anifrolumab for fatigue in lupus

This study tests whether a medicine called anifrolumab can help reduce severe tiredness (fatigue) in people with lupus. It is for adults whose lupus is mostly under control but who still feel very tired.

NCT05835310Recruiting· Phase 3
IV anifrolumab for active lupus in children

This study tests whether an intravenous medicine called anifrolumab can safely improve active systemic lupus (SLE) in children. If you qualify, you may receive the study treatment and be closely monitored for safety and lupus symptoms.

Phoenix, Arizona

Hear when a new Systemic Lupus Erythematosus trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.