Pimavanserin to improve sleep in veterans with PTSD
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a veteran age 18 to 64 (men and women can join).
- You have chronic insomnia for at least 3 months, with symptoms happening about 3 nights per week and affecting daytime functioning.
- Your insomnia severity score is in the moderate range (ISI total score 15).
- You have clinically significant PTSD symptoms based on a PTSD checklist score (PCL-5 around the PTSD cutoff).
- You can follow the study plan and agree not to start other insomnia or PTSD treatments during the study.
- You will need to avoid some sleep/psychiatric medicines before enrollment (as instructed), and for pregnancy-capable people you must use reliable pregnancy prevention.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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