Clin2
NCT05443841Possibly a fitRecruiting

Pleural lavage test to guide surgery in resectable esophageal cancer

Esophageal Cancer

Part of Cancer, Digestive system clinical trials.

This trial studies whether washing fluid from around the lungs (pleural lavage) can show cancer cells and help predict outcomes for people with operable esophageal cancer. It may add useful information before surgery to support better treatment decisions.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
385 people
Ages
Any age
Study type
Observational

Who can take part

  • You have confirmed esophageal cancer based on a pathology test (biopsy or similar) before starting treatment.
  • Your cancer is considered resectable, meaning surgeons think it can be fully removed (aiming for an R0 resection).
  • Your scans show no distant spread (M0) and lymph node status can be N0 to N3.
  • You do not have a history of other past cancers (besides the current esophageal cancer).
  • You have not had endoscopic scar-removal procedures called ESD or EMR.
  • Doctors can safely do the pleural lavage procedure—there should be no lung-covering adhesions that prevent it.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06914011Not yet recruiting· Phase 3
Adjuvant chemotherapy for esophageal cancer guided by blood test

This trial tests whether giving chemotherapy after surgery, based on a blood test that finds tiny bits of cancer DNA, can improve outcomes for people with esophageal squamous cell carcinoma. The blood test helps decide who might benefit from extra treatment.

NCT06304350Recruiting· Phase 2
Pembrolizumab plus chemo before surgery for esophageal cancer

This trial tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (given before surgery) can help shrink stage II/III esophageal cancer. The goal is to make surgery more likely to remove all cancer and improve outcomes.

Shanghai, Shanghai Municipality
NCT05704530Recruiting
Liquid blood tests for early esophageal cancer

This trial studies how well “liquid biopsy” blood tests can work in people with newly diagnosed, operable esophageal cancer. It may help doctors monitor the cancer and guide treatment planning alongside standard care.

Antwerp
NCT07780721Not yet recruiting· Phase 2
Study of immunotherapy and chemotherapy before surgery for esophageal cancer

This trial tests a combination of an immunotherapy drug (adebrelimab), an immune-boosting agent (thymalfasin), and standard chemotherapy given before surgery for esophageal cancer. The goal is to see if this combination can shrink the tumor and improve outcomes after surgery.

Putian, Fujian
NCT05706558Recruiting
Study of esophageal cancer surgery records

This study looks back at past patients’ medical and pathology records from esophageal cancer surgeries. It may help improve how doctors understand which advanced tumors should be treated, by reviewing outcomes in specific tumor stages.

New York, New York
NCT06508229Not yet recruiting· Phase 2
Treatment before surgery for esophageal cancer

This trial tests a combination of three medicines (immunotherapy plus two chemotherapy drugs) given before surgery to shrink esophageal cancer. The goal is to make the tumor smaller and easier to remove completely, potentially improving the chance of a cure.

Hear when a new Esophageal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.