Clin2
NCT05467683Possibly a fitRecruiting

Breathing CO2 test to predict which anxiety therapies won’t work

Obsessive-Compulsive DisorderPost Traumatic Stress DisorderGeneralized Anxiety DisorderSocial Anxiety DisorderPanic Disorder

Part of Mental health clinical trials.

This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
600 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have a DSM-5 diagnosis of panic disorder, social anxiety, generalized anxiety, OCD, or PTSD
  • Your anxiety severity score is at least 8 on the OASIS questionnaire
  • You are between 18 and 70 years old and can give informed consent
  • You can complete study assessments in English
  • You are not pregnant or breastfeeding
  • You don’t have medical problems that make CO2 breathing or fast breathing unsafe

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05427708Recruiting
Breathing training to reduce anxiety symptoms

This study tests whether specific respiratory (breathing) training can reduce anxiety symptoms and fear responses. It may help people who have several kinds of anxiety or trauma-related anxiety, especially if they are not on anxiety medicines or only stable on them.

Austin, Texas
NCT07753330Recruiting
Anxiety treatment study

This study tests a new type of therapy that focuses on facing fears to help reduce anxiety. It may be a good fit if you have an anxiety disorder and are looking for treatment.

Santiago, Santiago Metropolitan
NCT04701723Recruiting
Breathing training to help after trauma stress

This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.

Saint-Paul
NCT06773585Not yet recruiting
Anxiety disorder treatment response and recovery study

This study looks at what factors help people with anxiety disorders respond to treatment and recover. It uses virtual reality and other assessments to understand your anxiety better, which may help guide better treatments in the future. As a participant, you will receive thorough evaluations and may be part of either the anxiety group or a healthy comparison group.

Seoul, Jongno-gu
NCT03826693Recruiting· Phase 2
Nitrous oxide trial for obsessive-compulsive disorder symptoms

This Phase 2 pilot study tests whether breathing nitrous oxide (laughing gas) can reduce symptoms of obsessive-compulsive disorder (OCD). It compares what happens during a treatment-free period and then during the study treatment to see if symptoms improve.

Stanford, California
NCT06678295Recruiting
CBT for social anxiety or body dysmorphic disorder

This study looks at how individual factors affect the success of cognitive behavioral therapy (CBT) for social anxiety or body dysmorphic disorder. You'll have therapy sessions and brain scans to see what works best for people like you.

Seattle, Washington

Hear when a new Obsessive-Compulsive Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.