Clinical trials
Obsessive-Compulsive Disorder clinical trials
Below are recruiting obsessive-compulsive disorder clinical trials, each written for real people, not researchers. We’re tracking 107 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05048251RecruitingTeam says not enrolling
Targeted brain stimulation for OCD with contamination symptoms
This study tests a personalized brain-stimulation approach to help people with obsessive-compulsive disorder (OCD) focused on contamination worries. If you have the “contamination” type of OCD and meet the safety and medication rules, you may be able to join and see whether this targeted treatment reduces symptoms.
Belmont, MassachusettsAges 18–55 - NCT05931913Recruiting
TMS plus exposure therapy for teenage OCD
This study tests whether combining transcranial magnetic stimulation (TMS) with exposure therapy can help reduce OCD symptoms in young people aged 12-21. TMS is a non-invasive brain stimulation technique. The study aims to see if this combination is more effective than exposure therapy alone.
Minneapolis, MinnesotaAges 12–21 - NCT07774481Recruiting
Anxiety skills study for Ohio residents
This study tests an anxiety management program that you can use on your smartphone. It aims to help reduce anxiety symptoms and improve daily functioning.
Columbus, OhioAges 18 years+ - NCT07763977Enrolling by invitation
Vitamin D and iron study for obsessive-compulsive disorder
This study tests whether vitamin D and iron levels affect brain function linked to self-control in people with OCD. It may help find new ways to improve treatment.
Guangzhou, GuangdongAges 14–45 - NCT05377125Recruiting
Training brain skills to reduce urges in OCD spectrum
This study tests a training program meant to improve “response inhibition,” the brain’s ability to pause before acting on unwanted urges. It may help people with OCD-spectrum conditions like obsessive-compulsive disorder, trichotillomania (hair pulling), or skin picking by targeting brain control of impulses.
Milwaukee, WisconsinAges 18–60 - NCT06102941Recruiting
Cognitive training for OCD in kids aged 8 to 12
This study tests a cognitive training program to help young children with OCD. It's designed for kids whose OCD is their main problem and who are not currently on medication or in other therapy.
New York, New YorkAges 8–12 - NCT05609916Recruiting
CBT therapy to help kids stop OCD medicine
This trial studies whether adding structured talk therapy (CBT) can help some children with obsessive-compulsive disorder (OCD) reduce and potentially stop their OCD medicine. It’s designed for kids who are still having meaningful symptoms despite being on an OCD medication long enough.
Houston, TexasAges 7–17 - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT07124780Recruiting
Study to help people with OCD find work
This study tests whether a type of talk therapy (called cognitive behavioral therapy, or CBT) can help people with OCD find and keep a job. If you're unemployed, live in New York State, and want to work, this program may be a fit for you.
New York, New YorkAges 18–60 - NCT06816511Enrolling by invitation
Focused ultrasound study for hard-to-treat OCD
This trial tests if a non-invasive ultrasound treatment can help people with obsessive-compulsive disorder (OCD) that hasn't improved with standard therapies. You must have had OCD for at least five years, have severe symptoms, and have tried multiple medications and cognitive-behavioral therapy without enough benefit.
TaipeiAges 18–65 - NCT07725926Recruiting
Combining therapy techniques for tic-like OCD
This study tests a therapy that combines two approaches—one for tics and one for OCD—to help people whose OCD feels like it's linked to tics. The goal is to see if this combined treatment reduces distressing urges and repetitive behaviors.
London, LondonAges 18–65 - NCT07347405RecruitingPhase 1
Psilocybin Whole Mushroom for OCD Treatment
This trial tests a whole-mushroom version of psilocybin as a potential treatment for OCD that hasn't improved with standard therapies. Participants receive psilocybin in a controlled setting and are monitored closely for safety and changes in symptoms.
Tucson, ArizonaAges 18 years+ - NCT07701616Recruiting
Digital mindfulness therapy for obsessive-compulsive disorder
This study tests a smartphone-based mindfulness program to help people with obsessive-compulsive disorder (OCD) reduce their symptoms. If you have OCD and are between 12 and 65 years old, you may be able to join.
Changsha, HunanAges 12–65 - NCT07704632Recruiting
Focused ultrasound helmet for severe OCD
This study tests whether a special helmet that uses focused ultrasound can safely change brain activity in adults with severe OCD that hasn't improved with other treatments. It may offer a new option for people who have not found relief from medications or therapy.
Toronto, OntarioAges 18–85 - NCT03826693RecruitingPhase 2
Nitrous oxide trial for obsessive-compulsive disorder symptoms
This Phase 2 pilot study tests whether breathing nitrous oxide (laughing gas) can reduce symptoms of obsessive-compulsive disorder (OCD). It compares what happens during a treatment-free period and then during the study treatment to see if symptoms improve.
Stanford, CaliforniaAges 18–65 - NCT03918577Recruiting
Caloric stimulation to help thinking in OCD spectrum
This trial studies whether a gentle inner-ear stimulation can change how people experience troubling thoughts in OCD-spectrum conditions. If you have strongly held intrusive worries related to these conditions, the study may help see whether this approach can reduce their impact.
Stanford, CaliforniaAges 18–65 - NCT03953014Recruiting
Genetic study of antidepressant side effects in young people
This trial studies whether genes (using a saliva sample) can help explain why some young people feel more “disinhibited” after taking antidepressants like SSRIs. If you’ve had depression, anxiety, or OCD and have used an SSRI, your information and genetics may help improve how antidepressants are chosen and monitored.
Calgary, AlbertaAges 6–17 - NCT04071990Recruiting
Family therapy for OCD together, testing CBT with guidance
This trial studies whether involving family members in cognitive behavioral therapy (CBT) for OCD helps people improve symptoms. It requires both you and a family member to attend sessions together and follow the study plan.
GhentAges 18–65 - NCT04131829RecruitingPhase 1/Phase 2
Brain scan study to predict fluoxetine response in OCD
This study looks at how brain networks change before and after starting fluoxetine (an SSRI antidepressant) in people with obsessive-compulsive disorder (OCD). It also compares these brain scan patterns with people without OCD to help predict who may respond to treatment.
New Haven, ConnecticutAges 18–65 - NCT04480918Recruiting
Registry for people with depression or bipolar to receive psychiatry care
This is a patient registry that enrolls people being evaluated for treatment options from an Interventional Psychiatry Service. It helps track patients with depression, bipolar disorder, or treatment-resistant OCD who are suitable for these psychiatry treatments.
Iowa City, IowaAges 18–99 - NCT04539951RecruitingPhase 2
Trial for newly treated obsessive-compulsive disorder
This phase 2 study tests an OCD treatment strategy for people who have not yet had OCD medications or recent OCD therapy. It aims to reduce OCD symptoms, especially for those with moderate-to-severe symptom levels.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT04723485Recruiting
Study of obsessive-compulsive disorder in youth
This study looks at obsessive-compulsive disorder (OCD) in children and young adults to better understand and document treatment and experiences. It may help researchers learn what supports work best for young people with OCD.
Zurich, Canton of ZurichAges 4–18 - NCT04730011Recruiting
Short intensive therapy for kids with obsessive-compulsive disorder
This trial studies a short, intensive therapy program for children and teens with obsessive-compulsive disorder (OCD). It may help by testing whether a focused treatment schedule can improve OCD symptoms.
Zurich, Canton of ZurichAges 8–18 - NCT04882839RecruitingPhase 2
Therapy with psilocybin for severe OCD symptoms
This Phase 2 study tests whether psilocybin-assisted psychotherapy can reduce symptoms in adults with severe, treatment-resistant OCD. It also focuses on safety and whether this approach is practical to run.
BeershebaAges 18–65
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Obsessive-Compulsive Disorder trials by city
Studies with a site in or near these metro areas.
Obsessive-Compulsive Disorder trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for obsessive-compulsive disorder?
- Yes. Clin2 currently lists 107 recruiting obsessive-compulsive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obsessive-compulsive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obsessive-compulsive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.