Testing breast radiation after lumpectomy with or without hormone pills
Part of Cancer, Skin clinical trials.
This Phase 2 trial compares different “after-surgery” treatment plans for certain older women with hormone-sensitive early breast cancer. It looks at whether a standard hormone-pills approach or a faster, smaller-area radiation approach (given after lumpectomy) works best to prevent cancer coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman age 65 or older with a new invasive breast cancer found for the first time
- Your tumor is small (T1) and grade 1 or 2 (not high-grade)
- Your cancer tests positive for estrogen and progesterone receptors (ER/PR) and is not HER2-positive
- Your cancer has not spread to lymph nodes that are nearby (N0) and does not have lymphovascular invasion (LVSI)
- After lumpectomy, the surgical edges/margins are at least 2 mm, and your surgeon’s plan fits “APBI” (accelerated partial breast irradiation)
- You cannot be on chemotherapy during the study, and you must be able to stop hormone-blocking drugs (if currently taking) within 30 days of randomization
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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