Breast re-irradiation after second lumpectomy
Part of Cancer, Skin clinical trials.
This trial tests whether giving a second round of radiation to the breast after a lumpectomy for a recurrence is safe and effective. It is for people with a specific type of breast cancer (ER+HER2-) who meet strict criteria regarding prior radiation and tumor characteristics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 40 years or older.
- Your breast cancer is ER+ and HER2- (hormone-sensitive and HER2-negative).
- You had radiation to the same breast at least 18 months ago, and the total dose was not too high.
- Your cancer has come back in the same breast but is small (less than 3 cm), has not spread to lymph nodes, and was removed completely.
- You have a low-risk Oncotype score (less than 26 if you are postmenopausal, or less than 16 if you are premenopausal).
- You are not pregnant, do not have a BRCA mutation, and do not have other serious health conditions like lupus or another cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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