Tested medicine for children with cerebral malaria
Part of Brain & nervous system, Infections clinical trials.
This early-stage study tests how a medicine (involving ondansetron and ceftriaxone) works in people with malaria. It especially focuses on children with cerebral malaria to see if it can improve safety and early effectiveness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your child) must sign a consent form before starting the study
- You must have a confirmed malaria test (blood smear) showing the malaria parasite
- For children (12 months to 14 years): you likely have cerebral malaria signs, like a very low coma score and no other clear cause
- Your blood tests must be within study limits for anemia, kidney function, and liver enzymes
- You must not be pregnant or trying to become pregnant (pregnancy testing required if able to become pregnant)
- You cannot have allergies to ondansetron or ceftriaxone
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new experimental antimalarial drug (GSK3772701) to see if it can safely and effectively treat uncomplicated malaria caused by P. falciparum parasites. You would receive the study drug by mouth and be monitored closely with blood tests and heart rhythm checks.
This Phase 1 study tests how safe a combination oral medicine (ZY19489 with ferroquine) is in adults who carry malaria in their blood but have no symptoms. It also studies how the body absorbs and processes the medicines.
This study looks at severe malaria in children from remote areas. It compares children with malaria, children with other severe fevers, and those with uncomplicated malaria to improve treatment in hard-to-reach villages.
This study compares a combination of three medicines to treat uncomplicated malaria, to see if it works as well and is as well tolerated as a two-medicine combination. You may join if you have a specific type of malaria infection in a mild form and meet safety requirements.
This study tests a malaria treatment called PDMC in children under 10 who are in the hospital with severe anemia or severe malaria. It aims to see if this treatment can help prevent further health problems.
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
Hear when a new Malaria, Cerebral trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.