Clin2
NCT05481619Possibly a fitRecruiting

Vedolizumab study for ulcerative colitis and gut changes

Ulcerative Colitis

Treatments studied

Part of Digestive system clinical trials.

This trial tests whether vedolizumab helps people with moderate-to-severe ulcerative colitis and what changes happen in the gut microbiome (the community of helpful bacteria in your intestines). You may be able to join if you’re an adult with ulcerative colitis who has not used vedolizumab before and haven’t taken certain gut-affecting medicines recently.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
30 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You’re 18 years old or older and have moderate-to-severe ulcerative colitis
  • You have a doctor’s recommendation to start vedolizumab
  • You have never taken vedolizumab before
  • You have not used biologic medicines before, or you stopped them more than 12 weeks ago
  • You have not taken antibiotics or probiotics in the last 4 weeks
  • You can fully take part in the study on your own and agree to sign consent

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06581328Recruiting· Phase 4
Study of vedolizumab for ulcerative colitis or Crohn's disease

This study tests a medication called vedolizumab for people with moderate to severe ulcerative colitis or Crohn's disease. The goal is to see how well it works in a regular community setting, and it may help control symptoms if other treatments haven't worked.

Birmingham, Alabama
NCT06609447Recruiting· Phase 4
Probiotic with vedolizumab for moderate ulcerative colitis

This study tests whether adding a special probiotic (VSL#3) to vedolizumab helps people with moderate ulcerative colitis more than vedolizumab alone. You may qualify if you are already planning to start vedolizumab and haven't responded well enough to other treatments.

Beijing, Beijing Municipality
NCT06100289Recruiting· Phase 3
Study of vedolizumab for kids with ulcerative colitis or Crohn's disease

This trial tests vedolizumab, a biologic medicine that reduces inflammation, in children and teenagers who have moderate to severe ulcerative colitis or Crohn's disease and have not responded well to other treatments.

Phoenix, Arizona
NCT05442567Recruiting· Phase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s

This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.

Mobile, Alabama
NCT07665294Not yet recruiting· Phase 4
Combination herbal supplement and vedolizumab for ulcerative colitis

This study tests whether adding a herbal supplement called CurQD to the standard treatment vedolizumab can help control ulcerative colitis symptoms better than vedolizumab alone. It aims to see if the combination reduces inflammation and improves quality of life for people with active disease.

New York, New York
NCT06405087Recruiting· Phase 3
Long-term study of vedolizumab for children with IBD

This study is for children and teenagers with ulcerative colitis or Crohn's disease who have already completed a previous vedolizumab study and are doing well. It will look at the long-term safety and effectiveness of continuing vedolizumab treatment.

Phoenix, Arizona

Hear when a new Ulcerative Colitis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.