Spevatamig for advanced stomach, pancreas, or bile duct cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new drug called Spevatamig (PT886), alone or with different chemotherapy and/or immunotherapy combinations, for people with certain advanced stomach, pancreatic, or bile duct cancers. The goal is to see if it shrinks tumors and is safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced (cannot be removed by surgery) gastric, gastroesophageal junction, bile duct, or pancreatic cancer that has spread or cannot be removed.
- You have already had at least one standard treatment for advanced disease, or standard treatment is not an option for you.
- You are 18 years or older and can sign a consent form.
- You are able to provide a tumor tissue sample (preferably fresh or stored) for testing.
- You have good daily activity (ECOG score 0 or 1 — able to care for yourself).
- You are not pregnant or nursing, and if you could become pregnant, you agree to use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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