Tizanidine to prevent frequent migraine attacks
Part of Brain & nervous system clinical trials.
This Phase 3 trial tests tizanidine to help prevent migraine attacks. If you have frequent migraine with or without aura, it compares tizanidine against placebo while tracking your headaches in diaries.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–65 years old
- You have migraine (with or without aura) for at least 1 year, and your first migraine started before age 50
- In the last 3 months, you had 4 or more migraine days per month but fewer than 15
- Your overall headache days are fewer than 15 days per month, and you meet diary rules during a baseline period
- You must be able and willing to complete electronic headache diaries and follow study visits, and sign consent
- If you can get pregnant, you must agree to reliable birth control during the study and for 28 days after the last study dose
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing new ways to treat migraine attacks. It is for adults in Denmark who have migraine on a few days each month and have used triptan rescue medicines.
This study tests whether a substance called CGRP (a protein linked to migraines) can safely trigger a migraine with aura in people who already have this condition. You'll receive an infusion and be monitored to see how your body responds.
This study tests whether amiloride can reduce how often migraine aura happens. It’s a proof-of-concept early study, meaning the main goal is to see if the approach seems to work and is safe for people with frequent aura.
This trial tests a type of acupuncture called Fu's Subcutaneous Needling (FSN) to see if it helps people with migraine without aura. It compares FSN to a common migraine prevention medication to find out which works better and why.
This study tests a medicine called rimegepant to see if it helps prevent migraines. If you have migraine at least 4 days per month, this might be for you.
This trial tests two new migraine medicines, rimegepant and zavegepant, given to people in the emergency department to see how well they work for stopping a migraine headache quickly.
Hear when a new Migraine Without Aura trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.