Clin2
NCT07667621Possibly a fitNot yet recruiting

Migraine medicines in the emergency department

MigraineMigraine DiseaseMigraine in AdultsMigraine HeadacheAcute MigraineMigraine Without AuraMigraine With Aura

Treatments studied

Part of Brain & nervous system clinical trials.

This trial tests whether a new class of migraine medicines, called gepants, can relieve migraine pain quickly when given in the emergency department. If you're having a migraine and haven't taken pain medication recently, you might be able to join.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old and able to understand and agree to the study.
  • You must be in the emergency department with a migraine headache that started more than 48 hours after your last headache.
  • You must be willing to answer a few short phone calls after you leave the hospital.
  • You must be able to speak English or Spanish.
  • You cannot have taken any migraine or pain medication within the last hour before the study drug is given.
  • You cannot have used certain migraine drugs (CGRP-targeting medicines) in the past, or have serious heart, liver, kidney, or blood vessel problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05903027Recruiting
Testing gepant migraine treatment for better side effects

This trial studies how well a “gepant” medicine works for different types of migraine and how tolerable it is. It may help if you have frequent migraines and you can keep a headache diary as the study asks.

Florence
NCT06401642Recruiting· Phase 4
Zavegepant for acute migraine with CGRP preventives

This study tests how well a new acute migraine medicine, zavegepant, works and is tolerated in people who are already taking a CGRP-targeting preventive medication. It may help you find an effective treatment when you get a migraine attack.

Phoenix, Arizona
NCT07861412Not yet recruiting
Nasal spray for acute migraine attacks

This study tests a nasal spray called zavegepant to see how well it treats migraine attacks quickly. It may help people who have frequent migraines and need a fast-acting treatment.

NCT06409832Recruiting
Study of rimegepant for migraine prevention

This study tests a medicine called rimegepant to see if it helps prevent migraines. If you have migraine at least 4 days per month, this might be for you.

Florence, Florence
NCT06728345Not yet recruiting
Rimegepant for preventing migraines in women

This study tests whether rimegepant, a migraine medication, can help prevent migraines in women. It looks at how well it works in real-life settings for women who have frequent migraines.

NCT06428838Enrolling by invitation· Phase 3
Add-on migraine treatment for emergency room visits

This study tests an add-on migraine medicine (eptinezumab) given in the emergency room to quickly relieve a migraine attack, in addition to the usual care. It aims to see if this approach reduces pain and prevents the migraine from coming back.

New Westminster, British Columbia

Hear when a new Migraine trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.