Vaginal seeding to change a baby’s early gut microbes
This early-phase study looks at whether swabbing a mother’s vagina during a planned C-section (“vaginal seeding”) can help shape a newborn’s early respiratory and gut microbes. The goal is to see if this approach is safe and may influence early-life breathing health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are the pregnant patient, age 18–40, and you can consent and attend visits
- You are having one baby (singleton pregnancy) with 37+ weeks and a planned C-section at Vanderbilt
- You had at least 3 prenatal visits at Vanderbilt and had swabs taken at 36+ weeks for Group B strep (GBS) screening
- No lab signs this pregnancy of Group B strep in the urine or swabs, and no other listed infections (like HIV, hepatitis B/C, syphilis)
- You can’t have certain past conditions (including prior baby with GBS infection, diabetes type 1 or 2, or genital herpes/HPV infections)
- Your baby should not need special delivery-room measures beyond routine care, and must not require NICU right away
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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