Clin2
NCT05534399Worth exploringNot yet recruiting

Antibiotics before bladder Botox when urine has bacteria but no symptoms

Urinary Tract Disease

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This study looks at whether giving antibiotics before botulinum toxin (Botox) injections into the bladder is helpful when you have bacteria in your urine but no symptoms. It is for people with multiple sclerosis or spinal cord injury who use self-catheterization.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
526 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have multiple sclerosis or a spinal cord injury.
  • You have overactive bladder (needing to go often or suddenly) that did not get better with medicines.
  • You already get botulinum toxin (Botox) injections into your bladder and they help you.
  • You use clean intermittent catheterization (a tube to empty your bladder) as your only way to empty your bladder.
  • You have bacteria in your urine without any symptoms of a bladder infection.
  • You have not taken antibiotics in the last month.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05998187Recruiting· Phase 3
Botox injections for fecal incontinence

This trial tests whether botulinum toxin (Botox) injections into the rectum can improve bowel control in people with active fecal incontinence. It aims to help those who haven't gotten better with standard treatments like diet changes or pelvic floor therapy.

Rouen, France
NCT04754737Recruiting
Testing antibiotic timing before bladder Botox injections

This study looks at whether taking antibiotics shortly before bladder Botox injections affects outcomes for people with overactive bladder. It aims to clarify what to do about antibiotic use before treatment.

Stony Brook, New York
NCT05519072Recruiting· Phase 4
Antibiotics before bladder Botox injections

This study looks at whether taking antibiotic medicine before bladder Botox reduces infection risk or complications. It’s for adults having bladder Botox treatments and who can safely take antibiotics by mouth.

Morristown, New Jersey
NCT06387329Recruiting· Phase 4
Antibiotic to prevent UTI after bladder Botox

This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.

Bethesda, Maryland
NCT04791579Recruiting· Phase 2
Preventing UTIs after Botox for neurogenic bladder

This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.

Edmonton, Alberta
NCT04444440Recruiting· Phase 4
Antibiotic prevention after bladder Botox for overactive bladder

This trial studies whether taking an antibiotic around the time of bladder Botox can lower the risk of urinary infections. It’s for women with overactive bladder who tried standard medicines but didn’t get enough relief.

Edmonton, Alberta

Hear when a new Urinary Tract Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.