Urinary Tract Disease clinical trials

Study on urinary symptoms in Chinese men over 40

This study looks at how common lower urinary tract symptoms are in Chinese men aged 40 and older. By participating, you can help researchers understand the impact of these symptoms and find better ways to help people like you.

Prevention options for recurring bladder infections in women

This trial studies different ways to prevent repeated bladder (urinary tract) infections in women. It may help people who keep getting these infections by testing safer or more effective prevention strategies.

Testing a prostate marker to predict response to finasteride

This study looks at a prostate test marker to understand who is more likely to benefit from 5-ARI medicines such as finasteride or dutasteride. If you have enlarged prostate symptoms and are getting a biopsy, the results may help doctors better choose or interpret 5-ARI treatment.

Study of infections after bladder removal

This observational study follows people after surgery to remove the bladder to learn how often infections happen and what they look like. It may help doctors better prevent and manage complications after this operation.

Exercise for older men with urinary problems

This study tests whether a special exercise program can help older men with urinary symptoms from an enlarged prostate. You'll either exercise at home with a heart rate monitor or receive health education for 6 months.

Single IV antibiotic dose for complicated UTIs in children

This trial studies whether giving just one dose of an intravenous (IV) antibiotic can safely treat complicated urinary tract infections (UTIs) in children. It aims to see if this shorter approach works as well as standard treatment while still preventing complications.

D-mannose to prevent recurrent urinary tract infections in older women

This study tests whether a simple sugar called D-mannose can help prevent repeat urinary tract infections (UTIs) in postmenopausal women. If you have had frequent UTIs, this trial will see if D-mannose is a good option to keep you infection-free.

Bladder training device for children with urinary problems

This trial tests a device that helps children with nighttime bedwetting, daytime urine leaks, or frequent urgent urination by teaching them to relax and control their bladder. It aims to improve symptoms without medication.

Lower Urinary Problems Database at Zurich Hospitals

This trial is a research database study collecting information from people who have bladder and urine flow testing. It may help doctors better understand lower urinary tract problems over time.

Fetal bladder procedure for severe blockage in a baby boy

This trial studies a fetal cystoscopy procedure to treat severe urinary tract blockage in a baby boy during pregnancy. It aims to see whether the procedure helps improve outcomes, but it requires specific pregnancy conditions and testing beforehand.

Optimizing Antibiotic Choice for Urinary Tract Infections

This study helps doctors choose the best antibiotic for urinary tract infections (UTIs) by looking at urine culture results. You'll be treated as an outpatient (at home) and monitored to see if your antibiotic is working well.

Ultrasound in children after a first bladder infection

This trial studies whether doing an ultrasound scan after a child’s first febrile urinary tract infection (UTI) is useful. The goal is to see which children might need further attention based on the scan.

Antibiotics by mouth only for young babies with urine infection

This trial studies whether giving antibiotics by mouth alone is enough to treat a urinary tract infection (UTI) in very young babies. It may help reduce the need for stronger or more invasive antibiotic approaches if you meet the study’s stability and urine-test requirements.

Urinary tract stones in children

This study looks back at the medical records of children who had urinary tract stones (kidney stones, bladder stones, etc.) treated at two hospitals in France between 2010 and 2022. It helps doctors learn more about how these stones affect children.

Using a new urine test to reduce unnecessary antibiotics for bladder infections

This study tests a new urine test (the UF-5000) to see if it can help doctors decide who really needs antibiotics for a bladder infection. The goal is to avoid giving antibiotics when they are not needed.

Spa care for kidney and urinary health in adults

This study tests whether a comprehensive spa program can help adults with chronic kidney or urinary tract conditions like infections, stones, or after surgery. It's designed for patients who have not responded well to standard medications.

Fecal Transplant to Prevent Repeat Urinary Tract Infections

This trial tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) can help prevent repeat urinary tract infections in women who have frequent infections.

High-dose antibiotics plus methenamine for chronic UTI in women

This trial compares a new treatment approach—high-dose antibiotics combined with methenamine hippurate—against standard care for women with chronic urinary tract infections (UTIs). It aims to find if the combination works better at relieving persistent symptoms like pain and frequent urination.

Sacituzumab govitecan with or without atezolizumab for rare GU cancers

This trial is testing a drug called sacituzumab govitecan, sometimes combined with atezolizumab (an immunotherapy), for rare cancers of the bladder, urinary tract, kidney, or penis. The goal is to see if these treatments work well for people whose cancers have not responded to other options.

Microbiota study in children with and without overactive bladder

This research study compares the bacteria in urine, around the genital area, and in stool between children with overactive bladder (frequent urgent need to urinate) and healthy children. The goal is to understand if differences in these bacteria might explain why some children develop overactive bladder.

Deep Endometriosis Affecting the Urogenital Tract: Long-term Outcomes and Impact on Renal Function

Brain activity study in children with overactive bladder

This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. It uses MRI scans to understand how the brain controls the bladder, which could lead to better treatments.

Gemcitabine and Mitomycin for High-Risk Upper Tract Cancer

This trial tests a combination of two chemotherapy drugs, gemcitabine and mitomycin, given directly into the kidney or ureter through a thin tube. It is for people with a high-risk but non-invasive form of upper urinary tract cancer that has not spread into deeper tissues.

HRS-8427 for complicated urinary tract infections

This trial tests a new antibiotic, HRS-8427, for people with complicated urinary tract infections (UTIs) or kidney infections. If you qualify, you would receive the study drug through an IV while in the hospital.