Clin2
NCT05539079Possibly a fitRecruiting

Long-term study of MGUS and how it may change over time

MGUS

Part of Blood & lymphatic clinical trials.

This study follows people with MGUS (a blood condition that usually does not cause symptoms right away) to learn how it progresses over the long term. If you have MGUS or might have it, your results may help doctors understand risk and changes over time.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
2,000 people
Ages
18 years and older
Study type
Observational

Who can take part

  • Be 18 years or older
  • Have confirmed or suspected MGUS
  • Agree to and be able to give informed consent
  • Have evidence of MGUS on blood tests (not just a borderline light-chain result)
  • Not have rapidly worsening abnormal protein levels or rapidly increasing light chains when joining

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06539832Recruiting
Gut bacteria and immunity in people with an abnormal blood protein

This study looks at how your gut bacteria (intestinal flora) and immune system relate to a condition called monoclonal gammopathy, where an abnormal protein is found in the blood. The trial will check samples from your blood, plasma, and stool to understand these connections.

Guanzhou, Guangdong
NCT06472830Enrolling by invitation
MGUS and multiple myeloma awareness screening study

This study screens adults aged 40 and older for early signs of MGUS (a benign blood condition) and multiple myeloma (a blood cancer). You'll fill out questionnaires about your health to help with early detection.

Rochester, Minnesota
NCT02269592Recruiting
Study blood marker changes in early, symptom-free blood cancers

This study follows people with early, “precursor” blood conditions to learn what changes in their blood or bone marrow signal progression. It may help doctors better predict outcomes and understand why some people develop symptom-causing cancer.

Boston, Massachusetts
NCT07057583Enrolling by invitation
Bone marrow cell study with a special carbon label

This study uses a special label (carbon 13) to track bone marrow cells in people with a pre-cancer condition called MGUS. It aims to learn how these cells work, which may help understand the condition better.

Rochester, Minnesota
NCT05361694Recruiting
Study aims to distinguish stable vs worsening early myeloma

This study looks at two different “precursor” conditions that can happen before multiple myeloma: MGUS and smoldering myeloma (SMM). Researchers want to better tell which cases are more likely to progress, using blood/urine tests and sometimes bone marrow tissue.

Miami, Florida
NCT06690593Recruiting
Gut Microbiome Study for Healthy Adults Age 45+

This study compares the gut bacteria of healthy adults (age 45+) with those who have a blood condition called monoclonal gammopathy. The goal is to see if gut bacteria patterns differ between the two groups.

Guanzhou, Guangdong

Hear when a new MGUS trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.