Microbiota transplant for advanced liver disease from alcohol
Part of Digestive system, Mental health clinical trials.
This trial tests whether giving a healthy mix of gut bacteria (an intestinal microbiota transplant) can improve outcomes in people with advanced liver disease caused by ongoing alcohol use. It may help rebalance the gut and support liver health, but participation depends on strict safety and diagnosis criteria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be older than 18 and able to sign consent in writing
- You have advanced liver disease caused by alcohol, and you are still drinking in a sustained way
- You have either declined regular alcohol-use treatment referrals before or tried them and they did not work
- You must NOT have recent/current alcoholic hepatitis or alcohol withdrawal symptoms
- You should not have severe liver illness markers (MELD score over 17) or significant confusion/memory issues from liver disease while on lactulose and/or rifaximin
- You cannot have certain stomach/intestine conditions (like Crohn’s/ulcerative colitis/celiac), recent severe swallowing trouble, or major infection/fever on the day of the procedure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether transplanting healthy gut bacteria can help prevent confusion and brain problems caused by liver disease. You would receive either the bacteria treatment or standard medications to see if it reduces these episodes.
This trial tests whether a fecal microbiota transplant (FMT) can help people with alcohol-related cirrhosis who are still drinking. It aims to see if FMT can reduce alcohol cravings and improve liver health.
This trial tests whether transplanting healthy gut bacteria (from donor stool) can improve outcomes in people with cirrhosis. If you have mild to moderate cirrhosis, you may be able to join.
This trial tests whether fecal microbiota transplantation (a controlled transfer of stool bacteria) is safe in people with severe alcoholic hepatitis. It aims to see if the treatment is tolerable and what risks may come with it, in addition to watching how liver illness changes.
This trial studies whether transferring healthy gut bacteria (from a donor sample) can improve outcomes for people with liver cirrhosis who have worsening complications. It may help by changing the gut microbiome, which can influence inflammation and liver health.
This trial studies fecal microbiota transplantation (a transfer of healthy gut bacteria from a donor) to help people with worsening liver failure. It may help by changing gut bacteria, which can affect complications like confusion, fluid buildup, infections, and kidney problems.
Hear when a new Cirrhosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.