Stool bacteria transplant for brain fog in liver disease
Part of Brain & nervous system, Digestive system, Hormones & metabolism clinical trials.
This study tests whether delivering healthy bacteria from a donor's stool (called a microbiota transplant) through a capsule can help people with cirrhosis and a history of hepatic encephalopathy. The goal is to improve brain function and reduce the risk of further confusion episodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Are 21 years or older.
- Have been diagnosed with cirrhosis (scarring of the liver), confirmed by a test or scan.
- Have had at least one episode of overt hepatic encephalopathy (severe confusion or change in thinking due to liver disease) in the past.
- Are currently on a stable dose of lactulose and/or rifaximin (medicines for brain fog) for at least 4 weeks.
- Are not on dialysis, don't have certain other bowel diseases, and haven't had serious complications recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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