Study of otoferlin hearing loss over time
Part of Brain & nervous system, Ear, nose & throat clinical trials.
This study follows people with hearing loss caused by changes (mutations) in the otoferlin gene to better understand how hearing and hearing-related test results change over time. It may help researchers prepare for future treatments by building a clear picture of the natural course of the condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have hearing loss in both ears from sensorineural causes (including auditory neuropathy).
- A genetic test shows you have a mutation in the otoferlin gene.
- You can (and agree to) follow all study visits and procedures after signing consent.
- At least one ear has certain hearing test results: otoacoustic emissions (OAE/“outer hair cell” test) present, and ABR results missing or abnormal within the last 12 months (or at the start).
- You do not have a cochlear implant, and you are not planning one in the next 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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