Lymph node removal plus standard treatment for cervical cancer
Part of Cancer, Women’s health & pregnancy clinical trials.
This Phase 3 trial tests whether removing specific lymph nodes in the lower pelvis and around the aorta, along with standard curative treatment, improves outcomes for people with locally advanced cervical cancer. It is mainly aimed at patients whose scans show pelvic lymph nodes involved but not clearly cancer in the para-aortic nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have newly diagnosed cervical cancer proven by biopsy (squamous, adenocarcinoma, or adenosquamous).
- Your scan (FDG-PET/CT) before treatment shows cancer in pelvic lymph nodes but no clear cancer in the para-aortic area (with only uncertain/common-iliac/nearby nodes allowed).
- Your cancer stage is FIGO IIIC1, and the highest involved lymph node is below the common iliac split on both sides.
- You can receive curative (aimed at cure) pelvic radiation and cisplatin-based chemotherapy, and your health status is good (ECOG 0–1).
- You are able and willing to follow the study plan, including scans and follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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