Test gut bacteria treatment for weight loss in pancreatic cancer
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This study looks at how changing the gut microbiome (gut bacteria) may help people with pancreatic cancer regain strength and slow or reverse cancer-related weight loss (cachexia). It also studies gut bacteria differences in people with pancreatic cancer who are losing weight versus those whose weight is stable, and in healthy volunteers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have pancreatic adenocarcinoma that is newly diagnosed (local or spread), or be classified as losing weight (cachexia) or weight-stable
- Start tube feeding or IV nutrition (parenteral nutrition) within the last 14 days, if you are newly diagnosed and meeting that pathway
- For the weight-loss (cachexia) group: have significant unplanned weight loss (or low BMI/sarcopenia as measured by a body scan like BIA)
- Not have had chemotherapy, radiation, or major pancreatic/related surgery already (like duodenopancreatectomy or biliary diversion)
- Be able to consent and speak enough French or German to understand the study; avoid antibiotics or immune-suppressing drugs for 30 days before joining
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how a person’s genetic variations may relate to cancer-related weight loss (cachexia) in pancreatic cancer. It may help researchers better understand who is most at risk and guide future treatments.
This study looks at differences in microbes (tiny organisms) using previously collected pancreatic tissue samples. It may help doctors understand how the microbiome relates to pancreatic diseases like pancreatic cancer.
This trial studies bacteria found inside pancreatic tumors to see if they can help diagnose or predict the course of the disease. You may be eligible if you have a suspected pancreatic cancer and need a special biopsy (EUS-FNB).
This study looks at the bacteria living in your gut and pancreas to understand how they might affect pancreatic cancer and precancerous changes. It is for people who are already scheduled for an endoscopic procedure to look at or treat a pancreatic lesion.
This trial tests a “multimodal” program meant to help people with cancer avoid developing cachexia, a condition that causes unwanted weight and muscle loss. It may help you stay stronger and maintain weight if you are not yet in advanced or rapidly worsening stages.
This study checks if advanced computer analysis of your tumor and body can predict severe weight loss and muscle wasting (cachexia) from pancreatic cancer. If you join, you may help doctors find earlier warning signs to improve treatment.
Hear when a new Pancreatic cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.