Improving movement control in children with dystonia
Part of Brain & nervous system clinical trials.
This study looks at how the brain processes movement in children with dystonia (a condition causing involuntary muscle contractions) to develop better treatments. It compares three groups: children with dystonia from genetic causes, those with cerebral palsy-related dystonia, and children without movement disorders.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 5 and 25 years old.
- If you have dystonia, it must be the primary condition, caused by genetics or unknown causes, or it must be from cerebral palsy linked to birth-related brain injury.
- If you have cerebral palsy, your MRI must show typical changes, and you must have minimal spasticity (stiffness).
- If you have genetic/idiopathic dystonia, you must have a normal MRI and no other neurological problems.
- You need to be able to understand and take part in the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how different types of dystonia (movement disorders) relate to genetics and brain findings from scans. You might help researchers understand why symptoms look different from person to person and what patterns may matter.
This study measures brain signals in children with dystonia to understand how the brain controls movement, with the goal of improving treatments like Deep Brain Stimulation (DBS). It also uses healthy children for comparison.
This study uses a new DNA reading method to find hidden genetic causes of dystonia. It is for people with dystonia who had standard genetic testing that did not find a cause.
This study tests how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy, a condition that causes muscle spasms. Researchers want to learn if a child’s genes affect how the medicine works and how the body processes it.
This study looks at brain activity patterns in people with dystonia who already have a deep brain stimulation (DBS) device. By recording brain signals during MRI and other tests, researchers hope to learn how DBS helps control movement.
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
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