Nasal rinse with allergy sprays vs regular nasal sprays
Part of Ear, nose & throat clinical trials.
This study compares two types of allergy-related nasal treatment: a rinse with azelastine and mometasone versus standard nasal sprays. It aims to see which approach works better for people with long-term (chronic) rhinitis over 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older and can follow the study treatment for 6 months.
- You have a diagnosis of chronic rhinitis (ongoing nasal allergy-like or runny/nasal symptoms).
- Your symptoms are not caused by another nose problem (like a deviated septum, nasal valve collapse, or chronic sinus infection).
- You do not currently use oral antihistamines or oral steroids, or you can complete a 4-week “washout” period before starting.
- You do not smoke or vape (including tobacco, marijuana, or other substances).
- You are not pregnant or breastfeeding, and you do not have a known allergy to the study medicines (azelastine or mometasone).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two methods of a procedure that targets nasal nerves to reduce chronic rhinitis symptoms. It may help people whose rhinitis is not caused by allergies.
This study compares two types of allergy medications added to a nasal steroid spray to see which works better for allergic rhinitis (hay fever-like symptoms). You'll help researchers understand if antihistamines or antileukotriene drugs are more effective when combined with your existing treatment.
This study tests a nasal spray made from mastic gum oil, combined with a lower dose of a standard steroid nasal spray, to treat chronic sinusitis (long-lasting inflammation of the sinuses). It may help reduce symptoms with fewer side effects from steroids.
This study tests whether rinsing the nose with budesonide (a steroid) can help adults with perennial allergic rhinitis whose symptoms are not well controlled by standard nasal sprays. It aims to see if this approach provides better relief.
This trial compares different ways to reduce rhinitis symptoms in people with moderate to severe nasal irritation. It may help find which treatment works best for you, depending on what type of rhinitis you have and your recent health and medication history.
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
Hear when a new Chronic Rhinitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.