Clin2
NCT06830109Possibly a fitRecruiting

Testing a nasal spray for stuffy nose relief

Nasal Obstruction

Treatments studied

Part of Ear, nose & throat, Lungs & breathing clinical trials.

This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have a history of a stuffy or blocked nose
  • You have tried a daily steroid nasal spray for at least 1 month and it did not help enough
  • You are willing to stop using other nose sprays (except saline) and decongestant pills
  • You either do not want surgery or cannot have surgery due to other health problems

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06580210Recruiting
Seawater spray with essential oils for stuffy nose

This trial tests a seawater and essential oil spray to clear a stuffy nose caused by a cold, sinus infection or allergies. The spray is meant to help you breathe easier without strong medicines.

Bayeux
NCT05494346Recruiting
Seawater nasal spray with essential oils for blocked nose

This trial tests whether a seawater nasal spray (with essential oils) is safe and works well for people ages 12+ who have sudden (acute) cold- or allergy-related nasal blockage. You may be able to join if you can use the spray as instructed and complete simple monitoring and questionnaires.

Blainville-sur-Orne
NCT07270302Not yet recruiting· Phase 1/Phase 2
Testing steroid spray treatment for chronic sinusitis

This study tests if using a nebulizer to deliver steroid spray can help people with chronic sinusitis (CRS) without prior sinus surgery. It focuses on improving symptoms like nasal congestion and facial pressure.

St Louis, Missouri
NCT02630121Recruiting· Phase 4
Nasal spray treatment to reduce mild sleep apnea congestion

This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.

Tampa, Florida
NCT05626621Recruiting· Phase 4
Nasal rinse with allergy sprays vs regular nasal sprays

This study compares two types of allergy-related nasal treatment: a rinse with azelastine and mometasone versus standard nasal sprays. It aims to see which approach works better for people with long-term (chronic) rhinitis over 6 months.

Evanston, Illinois
NCT07787494Not yet recruiting
Natural oil nasal spray with reduced steroid for chronic sinusitis

This study tests a nasal spray made from mastic gum oil, combined with a lower dose of a standard steroid nasal spray, to treat chronic sinusitis (long-lasting inflammation of the sinuses). It may help reduce symptoms with fewer side effects from steroids.

Armonia Centro Polispecialistico, Porto Mantovano

Hear when a new Nasal Obstruction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.