Buspirone for weak or missing esophagus contractions
Part of Digestive system, Ear, nose & throat clinical trials.
This study tests whether buspirone helps people whose esophagus does not squeeze properly (or doesn’t squeeze at all), causing swallowing problems. You would be assigned to buspirone or a placebo and monitored to see if symptoms improve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- Recent esophageal pressure testing (HRM within 3 months) showed weak or absent esophagus contractions with normal relaxation
- A camera look at your stomach and esophagus (endoscopy) within the last 12 months did not show a structural cause
- You have had trouble swallowing for at least 2 months, at least twice per week
- If you can become pregnant: you use reliable birth control and may need a pregnancy test before starting
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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