Letrozole after surgery for early uterine leiomyosarcoma
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This Phase 2 trial studies whether letrozole can help prevent uterine leiomyosarcoma from coming back after surgery. It focuses on people whose tumor shows estrogen receptor positivity.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your legal representative) sign consent and allow sharing of medical information.
- Your uterine leiomyosarcoma diagnosis is confirmed by pathology, and it was limited to the uterus (Stage I).
- Your tumor must test positive for estrogen receptor (ER positive) with ER staining over 10%.
- You had your uterus removed (hysterectomy) plus both ovaries and fallopian tubes removed within 12 weeks.
- You should have no measurable disease on scans/tests within 6 weeks (no tumors large enough to measure).
- You can swallow pills, are age 18 or older, and your overall health/lab results are strong enough (blood counts, liver/kidney tests).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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