Letrozole before surgery for postmenopausal women with early breast cancer
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests whether taking letrozole before surgery can help shrink tumors in postmenopausal women with a specific type of early-stage breast cancer that is hormone-receptor-positive, HER2-negative, and has spread to lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 69 years old.
- You have gone through menopause.
- You have been diagnosed with invasive breast cancer that is estrogen-receptor-positive and HER2-negative.
- Your tumor is 5 cm or smaller and has spread to 1–3 lymph nodes.
- You have not had hormonal therapy or chemotherapy for this breast cancer before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies treatments given before surgery for invasive breast cancer, aiming to shrink the tumor so surgery can be done more effectively. It may help some people need breast-conserving surgery or improve the chance of complete cancer removal.
This trial tests whether taking hormone therapy before surgery can improve outcomes for women with a specific type of breast cancer called lobular breast cancer. If you qualify, you would receive endocrine therapy for 6 months before your planned breast-conserving surgery.
This trial combines a short course of radiation before surgery with two oral medications (abemaciclib and letrozole) to treat early-stage, hormone-sensitive breast cancer. The goal is to see if this approach can shrink the tumor and improve outcomes.
This trial tests a new drug called SHR-A1811, given either alone or with the hormone therapy letrozole, before surgery for women with early-stage breast cancer that is hormone receptor positive and HER2-low. The goal is to see if this treatment can shrink the tumor before surgery.
This Phase 2 trial studies whether letrozole can help prevent uterine leiomyosarcoma from coming back after surgery. It focuses on people whose tumor shows estrogen receptor positivity.
This trial tests if giving hormone-blocking pills before surgery can help guide which treatments you need after surgery. It is for premenopausal women with early-stage, hormone-sensitive breast cancer.
Hear when a new Hormone Receptor-Positive, HER2-Negative, Node Positive Breast Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.