Using a kidney toxin level to predict heart effects in AKI
Treatments studied
Part of Infections, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at whether measuring indoxyl sulfate, a substance that can build up when kidneys are injured, can help predict how blood vessels and the heart are affected during acute kidney injury (AKI). It may help doctors understand who is at higher risk of heart-related problems while AKI is happening.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are currently hospitalized for acute kidney injury (AKI), in a regular unit or the kidney-focused intensive care unit.
- Your AKI is moderate to severe (KDIGO stage 2 or 3) and you are NOT on dialysis.
- Your AKI is due to a functional or organic cause (not the excluded causes like infection-related or blockage-related AKI).
- You do not have advanced long-term kidney disease with low kidney function (GFR under 45) and you do not have a kidney transplant.
- You are not pregnant and you are not receiving palliative (comfort-focused only) care.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether two substances in urine (TIMP2 and IGFBP7) can help doctors predict which patients with sepsis-related kidney problems will get worse. If these markers work, doctors could identify high-risk patients earlier and treat them more aggressively.
This study looks at whether certain blood tests can help predict if a patient in the intensive care unit (ICU) will develop acute kidney injury (a sudden loss of kidney function). It may help doctors detect kidney problems earlier and improve care for ICU patients.
This study looks at whether a blood protein called uromodulin can help predict how well people with sepsis and acute kidney injury will do. Sepsis is a serious infection, and acute kidney injury is a sudden drop in kidney function. The results may help doctors better understand and manage this condition.
This study tests whether a simple scoring tool can help doctors predict which ICU patients may develop kidney problems. It may help identify patients at risk early so they can receive closer monitoring.
This study looks for early signs in your blood or urine that can predict if you might develop kidney damage after heart or blood vessel surgery. It aims to help doctors identify high-risk patients earlier so they can protect their kidneys.
This study tests if a simple blood test (cystatin) can detect kidney damage earlier in people with chronic kidney disease who receive contrast dye for imaging. It could help doctors act faster to protect kidneys.
Hear when a new Acute Kidney Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.