GI-102 with or without pembrolizumab before brain surgery
Treatments studied
Part of Cancer clinical trials.
This trial is testing a new drug called GI-102, given alone or with pembrolizumab, before surgery for a type of brain tumor called glioblastoma or grade 4 astrocytoma. The goal is to see if these drugs can help shrink the tumor before it's removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a brain tumor (glioblastoma or grade 4 astrocytoma) that has come back or is growing, and you are able to have surgery to remove it
- You are willing to travel to the Mayo Clinic in Rochester, Minnesota for a biopsy and surgery
- Your kidney, liver, and blood cell counts are within acceptable ranges based on recent tests
- You are not pregnant, and you agree to use birth control for the study period
- You have not had certain treatments like chemotherapy or bevacizumab within the last 30 days, and your current steroid dose is low
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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