Vaccine for advanced cancers using your tumor’s targets
Treatments studied
Part of Cancer clinical trials.
This trial tests a personalized vaccine made from “neoantigens” (tumor-specific targets) to help your immune system fight advanced, inoperable solid tumors. It may be an option if standard treatment didn’t work or you stopped it and your health is strong enough for trial treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an advanced solid tumor that can’t be removed with surgery
- Your cancer has gotten worse after standard treatment, or you chose to stop other treatment, and it’s been more than 2 weeks
- You expect to live at least 3 months and are well enough for study visits (ECOG 0–2)
- You can sign informed consent, understand the study, and follow study procedures
- If you can become pregnant, you must have a negative pregnancy test and agree to reliable birth control during the study (and no pregnancy plans for 6 months)
- Your blood tests and organ function must be within allowed limits (liver, kidneys, blood counts), and heart rhythm testing (ECG) must be acceptable
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of a personalized vaccine (made from your tumor's unique markers), a drug that boosts your immune system (PD-1 inhibitor), and targeted radiation for people with advanced lung cancer that has progressed after initial treatment. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
This trial tests a personalized vaccine made from unique markers on your tumor cells (called neoantigens). The goal is to help your immune system fight the cancer more effectively. It is for people with advanced solid tumors who have not had gene therapy and are otherwise relatively healthy.
This trial tests a personalized vaccine made from your own cells to help your immune system attack tumor-specific targets. It may be an option if standard treatments have stopped working or caused side effects you can't tolerate.
This trial offers access to a personalized vaccine made from your tumor's unique markers (neoantigens). The goal is to train your immune system to fight your cancer. You may qualify if standard treatments have not worked or are not an option, and your doctor believes your 5-year survival chance is under 50%.
This trial tests a personalized mRNA vaccine made from your tumor's unique markers (neoantigens) to train your immune system to fight cancer. It is for people with advanced solid tumors who have not had gene therapy and are healthy enough for the vaccine.
This trial tests a personalized mRNA vaccine (RH125) designed to train your immune system to attack your cancer. It is for people with advanced solid tumors that have not responded to standard treatments, and it aims to see if the vaccine is safe and helpful.
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