Fisetin to slow worsening of sepsis in older hospital patients
Part of Infections clinical trials.
This Phase 2 trial tests whether a drug called fisetin can slow the progression of sepsis once you are admitted to the hospital. It may help patients recover more quickly or avoid worsening, but eligibility depends on how severe the illness is and what other treatments you need.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 65 or older
- You are hospitalized for a new acute infection that your care team believes is the main problem
- Your sepsis severity score (SOFA) is greater than 1
- You were admitted to the hospital (not just seen in an outpatient setting) and are expected to stay at least 48 hours
- You are not admitted to the ICU for this hospital stay
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether two medications—fenofibrate (used for cholesterol) or silymarin (a plant extract)—can help treat sepsis (a serious blood infection) when given early. Researchers want to see if either drug reduces complications and improves survival.
This trial tests whether a type of diabetes medicine (SGLT2 inhibitors) can help adults with sepsis, a life-threatening response to infection. If you have new-onset sepsis and can take oral medicine, you may be eligible.
This trial tests whether a diabetes medicine called dapagliflozin can help reduce inflammation in people with sepsis (a serious infection). If you are in the ICU with sepsis, this drug may improve your recovery.
This trial tests new and existing drugs in healthy volunteers to see how they affect the body's response to a substance that mimics sepsis. It helps researchers understand how these drugs might work in people with sepsis.
This trial looks at a new program to improve how doctors and nurses treat sepsis (a severe infection that can cause organ failure) in the emergency department. It aims to see if the program helps start the right treatments faster.
This trial is looking for patients who have an infection and are showing early signs of getting sicker, like a high warning score. It aims to find out if doctors can identify those at risk of sepsis sooner so they can start treatment earlier.
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.