Pre-surgery radiation to shrink soft-tissue sarcoma
Part of Cancer clinical trials.
This trial studies giving radiation before surgery to help control a soft-tissue sarcoma while keeping surgery as less extensive as possible. It may help shrink the tumor and improve what the surgeon can remove.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your diagnosis is confirmed as soft-tissue sarcoma (from tissue biopsy results)
- Your medical team believes you may be able to avoid amputation and have conservative (limb-sparing) surgery
- Your overall health is good enough for treatment (based on a standard performance score before starting)
- You have not had radiation to the same body area before
- You do not have certain medical problems related to collagen diseases, and you can understand and agree to the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a shorter course of radiation (just 5 days) before surgery for soft tissue sarcoma. The goal is to see if a brief, high-dose radiation schedule works as well as or better than the usual longer course—and may be more convenient for you.
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This trial studies a shorter-course proton radiation plan given before surgery for certain soft tissue sarcomas. The goal is to treat the tumor locally while helping surgery be safer or more effective.
This study tests a 5-day course of radiation before surgery instead of the usual 5 weeks. It may help people who face challenges like travel or tumor growth that make the longer schedule difficult.
This trial tests if a powerful type of radiation called carbon ion therapy, given before surgery, is safe and effective for treating soft tissue sarcoma. It may help shrink the tumor before it’s removed.
This trial tests combining anlotinib (a targeted therapy), doxorubicin (chemotherapy), and radiation given before surgery to shrink high-grade soft tissue sarcomas. The goal is to make the tumor easier to remove and improve outcomes.
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