Combination treatment aimed at clearing hepatitis B long-term
Treatments studied
Part of Digestive system, Infections clinical trials.
This Phase 2 study tests a combination treatment to help people with chronic hepatitis B stop having detectable hepatitis B surface antigen (called HBsAg). If successful, it may move you closer to a “functional cure,” meaning lower ongoing virus activity over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You agree to sign consent and follow all study visits and rules
- You are age 18 to 70 and within the required weight/BMI ranges
- You have chronic hepatitis B and have either never taken hepatitis B medicines (NAs-naive) or have taken them before (NAs-experienced)
- You can use effective birth control during the study and for 30 days after the last dose (for people who could become pregnant)
- You do not have known allergy to the study drug or its ingredients
- Recent medicines that strongly affect the liver (especially CYP3A4 medicines) and certain immune-suppressing or live vaccines are avoided
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 2 study tests a combination therapy to help people with chronic hepatitis B reach a “functional cure,” meaning the hepatitis B surface antigen (HBsAg) is lost for a sustained period. If you qualify, you’ll be closely monitored to see how well the treatment works and whether it’s safe for you.
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