Clin2
NCT05771402Possibly a fitRecruiting

Combination treatment aimed at clearing hepatitis B long-term

Chronic Hepatitis bAnti-PD-1 AntibodyPeg-IFNα

Treatments studied

Part of Digestive system, Infections clinical trials.

This Phase 2 study tests a combination treatment to help people with chronic hepatitis B stop having detectable hepatitis B surface antigen (called HBsAg). If successful, it may move you closer to a “functional cure,” meaning lower ongoing virus activity over time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You agree to sign consent and follow all study visits and rules
  • You are age 18 to 70 and within the required weight/BMI ranges
  • You have chronic hepatitis B and have either never taken hepatitis B medicines (NAs-naive) or have taken them before (NAs-experienced)
  • You can use effective birth control during the study and for 30 days after the last dose (for people who could become pregnant)
  • You do not have known allergy to the study drug or its ingredients
  • Recent medicines that strongly affect the liver (especially CYP3A4 medicines) and certain immune-suppressing or live vaccines are avoided

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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