Clin2
NCT05774704Possibly a fitRecruiting

Curcumin eye study for people with retinal amyloid deposits

BioavailabilityGut MicrobiomeSafety

This early-stage study tests whether curcumin (a natural plant compound) can affect eye changes in people who have amyloid deposits in the retina. It aims to see if the treatment is safe and possibly helpful for vision-related outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
60 people
Ages
40 years to 89 years
Study type
Interventional

Who can take part

  • You are between 40 and 89 years old.
  • You have amyloid (Aβ) deposits in the retina (the eye exam may be repeated after you consent).
  • You do not have known liver or kidney disease (based on what you report).
  • You have not used turmeric or curcumin products in the 2 weeks before starting the study.
  • You have not taken systemic antibiotics in the month before starting the study.
  • You do not have an allergy to black pepper, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03135327Recruiting
Eye scans study to compare brain and eye health

This study uses detailed eye imaging to look for patterns that may go along with conditions like Alzheimer’s disease, memory problems, multiple sclerosis, or eye/vascular issues. It may help researchers better understand how eye findings relate to health and disease.

Miami, Florida
NCT03403686Recruiting
Study eye treatment target for diabetic retinopathy

This study tests a new approach aimed at improving diabetic eye disease (diabetic retinopathy). It may help by changing inflammation and related processes in the eye, especially in people who have diabetes and eye changes.

Birmingham, Alabama
NCT07379177Not yet recruiting
How a curcumin supplement is processed in healthy adults

This study tests how a curcumin supplement (an extract from turmeric) moves through the body in healthy adults. It aims to see how the body processes it, which can help understand its effects and safety.

Xiamen, Fujian
NCT06514001Recruiting· Phase 2
Testing a new drug for Alzheimer's disease with eye scans

This trial tests an investigational drug called AMDX-2011P for people with Alzheimer's disease. It looks at whether the drug affects the retina, which may be linked to brain changes in Alzheimer's.

Phoenix, Arizona
NCT04697095Recruiting
Testing immune cells from specific AMD eye types

This study collects immune cells (from a blood sample) from people with certain types of age-related macular degeneration (AMD) and compares how long they live. It may help researchers understand how immune-related changes relate to AMD outcomes.

Lyon
NCT06626230Recruiting· Phase 1
Safety of curcumin for anal precancer

This study tests whether a curcumin (turmeric) suppository can safely treat anal precancerous changes called AIN 2 or AIN 3. It may be an option if you have high-grade cell changes and want to avoid more invasive treatments.

Atlanta, Georgia

Hear when a new Bioavailability trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.