Clin2
NCT06626230Possibly a fitRecruiting

Safety of curcumin for anal precancer

Anal High Grade Squamous Intraepithelial Lesion

Part of Cancer clinical trials.

This study tests whether a curcumin (turmeric) suppository can safely treat anal precancerous changes called AIN 2 or AIN 3. It may be an option if you have high-grade cell changes and want to avoid more invasive treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
48 people
Ages
30 years and older
Study type
Interventional

Who can take part

  • You are 30 years old or older.
  • You have a biopsy-confirmed anal precancer (AIN 2 or AIN 3) that hasn't been treated yet, or a Pap-like test showing high-grade cell changes (ASC-H or HSIL).
  • You are willing to fill out a daily study diary.
  • You do not have a serious chronic illness that is getting worse (like heart disease, severe lung disease, or uncontrolled diabetes).
  • You have never had anal cancer, and you are not pregnant or planning to become pregnant in the next 3 months.
  • You are not currently using or have not used intravenous drugs (except for medical reasons) or had alcohol abuse in the past year.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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