Longer vs shorter antibiotic prevention after pancreatoduodenectomy
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism, Infections clinical trials.
This trial compares a standard length of preventive antibiotics versus a longer course after Whipple surgery to see if it lowers infection risk without causing extra side effects. It targets people considered higher risk for contamination of bile during surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are having an elective Whipple procedure (pancreatoduodenectomy)
- Your surgery is considered higher risk for contaminated bile (for example, you had preoperative biliary drainage or you have an ampulla cancer)
- You are not pregnant
- You can safely take the trial antibiotics (no allergy or intolerance)
- You are not already planning antibiotic treatment for an infection before surgery (like cholangitis or a liver abscess)
- Your kidney function is normal enough for the study (eGFR is 60 or higher)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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