Clin2
NCT05790239Possibly a fitRecruiting

MDMA therapy sessions for veterans with PTSD

Post Traumatic Stress Disorder

Treatments studied

Part of Mental health, Pain clinical trials.

This Phase 2 trial tests whether therapy assisted by MDMA can reduce symptoms of moderate to severe post-traumatic stress disorder (PTSD) in eligible veterans. It includes supervised therapy sessions and extra study visits with video recording to track changes over time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Have current PTSD symptoms for at least 6 months (moderate to severe)
  • Be a veteran getting care through a VA center in the Greater Los Angeles area
  • Be able to read and speak English and swallow pills
  • Be willing to have study visits recorded on audio/video, including MDMA therapy sessions
  • Have an approved support person who can be contacted if you become unwell, and can stay with you during the therapy evenings if needed
  • Pass health checks (such as blood pressure/cardiovascular screening) and follow pregnancy/conception rules if applicable

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07569159Recruiting· Phase 2
MDMA-assisted therapy for veterans with PTSD

This study tests whether MDMA (a medication) combined with therapy can help veterans with post-traumatic stress disorder (PTSD). MDMA may help people process difficult memories and emotions more effectively during therapy sessions.

Rockville, Maryland
NCT07118839Recruiting· Phase 2/Phase 3
MDMA therapy for veterans with PTSD and alcohol use

This study tests whether MDMA-assisted therapy can help veterans who have both PTSD and alcohol use disorder. If you have tried a standard therapy before and want to reduce or stop drinking, this treatment may offer a new option.

West Haven, Connecticut
NCT07704762Not yet recruiting· Phase 2
MDMA-assisted therapy for PTSD in U.S. service members

This study tests whether MDMA (a drug that can help people feel safe and open during therapy) combined with talk therapy can reduce PTSD symptoms in active-duty service members, National Guard, and Reserve members. If you are struggling with PTSD that has lasted at least 6 months, this trial may offer a new treatment option.

NCT05732155Recruiting· Phase 2
MDMA-assisted therapy for war-related PTSD

This study tests whether combining MDMA with talk therapy can help people with post-traumatic stress disorder (PTSD) from war experiences. It involves both individual and group therapy sessions, and the medication is given during some sessions.

Afula
NCT07288151Recruiting· Phase 2
MDMA with Exposure Therapy for PTSD

This trial tests whether MDMA (the drug in ecstasy) combined with a type of talk therapy called massed exposure therapy can help treat PTSD. It may be an option if standard treatments haven't worked well enough.

Atlanta, Georgia
NCT06044675Recruiting· Phase 2
MDMA plus therapy for PTSD – a study with a partner

This study tests whether MDMA, combined with a type of talk therapy called CBCT (cognitive behavioral conjoint therapy), is more effective than CBCT alone for treating PTSD. You and a close partner will both participate in therapy sessions and take MDMA together.

Toronto, Ontario

Hear when a new PTSD trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.