Fecal transplant to treat rheumatoid arthritis symptoms
Treatments studied
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This study tests whether transferring stool from a screened healthy donor into the gut can improve rheumatoid arthritis (RA) in people whose RA is in remission or low activity. It’s mainly trying to change the gut bacteria to reduce RA symptoms or flare-ups.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older and have been diagnosed with RA.
- Your RA blood tests are positive for anti-CCP (ACPA) and/or rheumatoid factor (RF).
- Your RA treatment has been stable for more than 6 months, and your disease is currently in remission or low activity.
- You are not pregnant or breastfeeding.
- You have not used certain immune-suppressing medicines recently, such as high-dose oral steroids, IV steroids, biologics, or JAK inhibitors (within the stated time windows).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies fecal microbiota transplantation (a stool-based treatment) to improve symptoms and safety in people with certain gut and immune conditions. It aims to see whether changing gut bacteria can help you feel better.
This study tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria into your gut) can reduce inflammation and improve symptoms in people with inflammatory back pain (axial spondyloarthritis). It may help if your current treatments are not working well enough.
This Phase 1/2 study tests whether a fecal microbiome transplant (FMT) can reduce active inflammation in people with Crohn’s disease. It’s designed for people who currently have signs of active bowel inflammation and can attend regular procedure visits.
This trial tests whether transplanting stool bacteria into the colon (fecal microbiota transplantation) can improve ulcerative colitis symptoms in people with active, moderate to severe disease. If you qualify, the study team will also check that it’s safe for you and that you can safely undergo a scope exam.
This trial tests whether fecal microbiota transplantation (FMT) can safely and effectively treat mild to moderate ulcerative colitis over the long term. FMT involves transferring stool from a healthy donor to restore a healthy balance of gut bacteria.
This study tests whether a fecal transplant (transferring healthy bacteria from a donor into your gut) can improve bowel control problems that sometimes happen after rectal cancer surgery. If you have ongoing trouble with leakage or urgency, this treatment might help.
Hear when a new Arthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.