Study for BEST1-related macular eye disease
Part of Eyes & vision, Genetic & congenital clinical trials.
This trial is studying people with BEST1-associated vitelliform macular dystrophy, a genetic eye condition affecting central vision. It will involve several eye-related study visits over about three years, aiming to better understand the condition and how it is managed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your legal representative) can understand the study and sign informed consent
- A study eye specialist must confirm you have BEST1-associated vitelliform macular dystrophy
- You are able to attend all scheduled follow-up visits (4 visits over about 3 years)
- You can complete the eye exams and other study procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1/2 study tests a gene therapy treatment (BS01) in people with retinitis pigmentosa to try to improve or preserve vision. You may be a candidate if your vision in at least one eye is quite limited and you haven’t had certain gene therapies before.
This trial tests a gene therapy called OPGx-BEST1 injected under the retina to treat vision loss from Best vitelliform macular dystrophy or a related condition. It may help people with advanced disease who have a specific genetic change in the BEST1 gene.
This study will check if certain vision tests work well in people with retinal diseases like retinitis pigmentosa or Stargardt. Results will help design future trials.
This trial tests an experimental drug called IGT001 for people with retinitis pigmentosa, a genetic eye disease that causes vision loss. The goal is to see if it is safe and can help slow or improve vision.
This study builds a registry and tracks the natural history of rare retinal dystrophies while also testing people for disease-causing gene variants. It may help researchers better understand what causes retinal degeneration and how it progresses.
This study is looking at how people with inherited retinal disease that affects peripheral vision see and move around. It will test a new way to measure vision and navigation to see if it can help doctors understand how the disease affects daily life.
Hear when a new Retinitis Pigmentosa trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.