Gefapixant to study brain activity in chronic cough
Part of Lungs & breathing clinical trials.
This early study tests whether gefapixant changes brain activity related to cough in people with chronic cough that hasn’t improved with usual treatments. It may help researchers understand why chronic cough happens and how to better treat it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be able to read and sign consent, and be 18–65 years old.
- You must be a non-smoker for at least 5 years, and have no neurological disease history.
- Your cough must be ongoing for at least 1 year and not respond to treatments for causes like reflux, asthma, or nasal allergies.
- Your cough severity must be high at screening (at least 40 mm on a 10-point scale).
- You must be able to have an MRI scan (no unsafe metal implants and you can handle being in the scanner).
- You must not be pregnant, and you must not have serious allergy to chili (very rare), and you need to do the study in English.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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