Clinical trials
Chronic Cough clinical trials
Below are recruiting chronic cough clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07690059RecruitingPhase 2
Magnesium oral spray for chronic cough
This trial tests a magnesium salt oral spray (SC0032) for adults whose chronic cough has not responded to treatment or has no clear cause. It aims to see if the spray can reduce coughing frequency and improve symptoms.
BelfastAges 18–80 - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT07659860Recruiting
Lower Airway Changes in Chronic Cough
This study looks at changes in the lower airways of people with a long-lasting cough that hasn't improved with treatment. It aims to understand why some coughs persist, which may lead to better treatments.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT07070895Recruiting
Wellness app for chronic cough study
This trial tests a smartphone app and a smartwatch to help people with chronic cough that hasn't improved with standard care. You'll wear a watch to track your cough and use the app to learn management techniques.
Wilmington, DelawareAges 21 years+ - NCT06960759RecruitingPhase 2
Cough suppression therapy for chronic cough
This study tests a behavior-based therapy to help you gain control over a persistent cough that hasn't responded to other treatments. You will learn techniques to reduce coughing during a 4-week program.
Aurora, ColoradoAges 18–99 - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT06376448Recruiting
Chronic cough study using a new questionnaire
This study aims to better understand different types of chronic cough by using a new questionnaire. If you have had a cough for at least 8 weeks and do not smoke, you may be able to help.
Cottingham, East YorkshiureAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT07488598Recruiting
Behavioral therapy for hard-to-treat chronic cough
This trial tests a behavioral therapy for people whose chronic cough (lasting more than 8 weeks) hasn't improved with usual treatments like asthma or reflux medicine. You may join if your cough is triggered by things like talking, laughing, cold air, or irritants, and you have throat symptoms like irritation or hoarseness.
AsyutAges 18–50 - NCT06286163Recruiting
ATP and P2X3 in chronic cough patients
This study looks at how certain nerve receptors (called P2X3) and a molecule called ATP might be linked to inflammation in the airways of people with chronic cough. It compares chronic cough patients to healthy non-smokers to better understand the cause of cough and find new treatment targets.
LondonAges 30–70 - NCT06600646Recruiting
Study of energy production in airway cells for chronic cough
This study looks at how the cells lining your airways make energy and whether this is different in people with chronic cough that doesn't get better with treatment or has no clear cause. It may help doctors understand why some people cough and find new ways to treat it.
Hamilton, OntarioAges 18–80 - NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT07650084RecruitingPhase 3
Testing BLU-5937 for hard-to-treat chronic cough
This 24-week study tests whether a new medicine called BLU-5937 can help adults whose chronic cough hasn't improved with standard treatments. Chronic cough that lasts a year or longer can seriously affect quality of life, and this trial explores whether this drug might provide relief.
Leshan, SichuanAges 18–80 - NCT07582549RecruitingPhase 3
Treatment for children's persistent cough
This Finnish study tests whether two common medicines (a steroid inhaler and an antibiotic) can help children whose cough has lasted more than 4 weeks without an obvious cause. Researchers want to see if these treatments work better than doing nothing.
TampereAges 1–6 - NCT07085975RecruitingPhase 1
Safety of inhaled ATP cough challenges
This study tests how safe and repeatable an inhaled ATP cough challenge is. It first enrolls healthy adults, then people with chronic cough or mild asthma who have not used steroid inhalers recently.
Hamilton, OntarioAges 18 years+ - NCT05273190Recruiting
Using gentle larynx stimulation to treat chronic unexplained cough
This study tests whether stimulating the larynx (voice box area) can reduce cough that has lasted more than 8 weeks. It may help people whose cough is not clearly explained by infections, lung diseases, or other common causes.
Minneapolis, MinnesotaAges 18–88 - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT07868419RecruitingPhase 3
Nalbuphine tablets for chronic cough in pulmonary fibrosis
This trial tests an extended-release tablet called nalbuphine to reduce chronic coughing in people with idiopathic pulmonary fibrosis (IPF), a lung condition that causes scarring and often leads to a persistent cough. If you have IPF and have been coughing for at least 8 weeks, this study may help manage that symptom.
Wilmington, DelawareAges 40 years+ - NCT07671911RecruitingPhase 3
Cough relief for pulmonary fibrosis
This trial tests a new extended-release medicine, nalbuphine, to reduce chronic coughing in people with idiopathic pulmonary fibrosis (a lung disease that scars the lungs). It may help make cough less frequent and less bothersome.
Newport Beach, CaliforniaAges 40 years+ - NCT06542484Recruiting
Studying gefapixant for cough in kidney or bladder cancer
This study tests a medicine called gefapixant to see if it helps reduce chronic coughing in people with kidney or bladder cancer. You may qualify if your cough persists despite treatment and you have little to no smoking history.
Nagoya, Aichi-kenAges 18 years+ - NCT07232550Recruiting
Breathing study for children needing bronchoscopy
This study collects samples (like fluid from the lungs) during a planned bronchoscopy to look for new ways to understand and predict children's breathing problems. It might help if your child already needs this procedure for a medical reason.
WarsawAges Up to 17 years - NCT05086432Recruiting
Test sputum-guided care to reduce cough in lung scarring
This study uses analysis of mucus (sputum) to guide treatment with the goal of reducing long-lasting cough in adults with interstitial lung disease (ILD). You may be asked to provide sputum samples and may receive treatment decisions based on those results.
Hamilton, OntarioAges 18 years+ - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT07212439Recruiting
Monitoring coughs to detect worsening COPD early
This study tests if monitoring your cough sounds can help detect a sudden worsening of COPD (a lung condition) sooner. It aims to find early warning signs so you can get treatment faster.
Pamplona, NavarreAges 18 years+
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Common questions
- Are there clinical trials for chronic cough?
- Yes. Clin2 currently lists 24 recruiting chronic cough studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic cough trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic cough trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.