Clinical trials
Chronic Cough clinical trials
Below are recruiting chronic cough clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06960759RecruitingPhase 2
Cough suppression therapy for chronic cough
This study tests a behavior-based therapy to help you gain control over a persistent cough that hasn't responded to other treatments. You will learn techniques to reduce coughing during a 4-week program.
Aurora, ColoradoAges 18–99 - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT05813223RecruitingEarly Phase 1
Gefapixant to study brain activity in chronic cough
This early study tests whether gefapixant changes brain activity related to cough in people with chronic cough that hasn’t improved with usual treatments. It may help researchers understand why chronic cough happens and how to better treat it.
Parkville, VictoriaAges 18–65 - NCT06376448Recruiting
Chronic cough study using a new questionnaire
This study aims to better understand different types of chronic cough by using a new questionnaire. If you have had a cough for at least 8 weeks and do not smoke, you may be able to help.
Cottingham, East YorkshiureAges 18 years+ - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT07070895Recruiting
Wellness app for chronic cough study
This trial tests a smartphone app and a smartwatch to help people with chronic cough that hasn't improved with standard care. You'll wear a watch to track your cough and use the app to learn management techniques.
Wilmington, DelawareAges 21 years+ - NCT07659860Recruiting
Lower Airway Changes in Chronic Cough
This study looks at changes in the lower airways of people with a long-lasting cough that hasn't improved with treatment. It aims to understand why some coughs persist, which may lead to better treatments.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT06286163Recruiting
ATP and P2X3 in chronic cough patients
This study looks at how certain nerve receptors (called P2X3) and a molecule called ATP might be linked to inflammation in the airways of people with chronic cough. It compares chronic cough patients to healthy non-smokers to better understand the cause of cough and find new treatment targets.
LondonAges 30–70 - NCT06600646Recruiting
Study of energy production in airway cells for chronic cough
This study looks at how the cells lining your airways make energy and whether this is different in people with chronic cough that doesn't get better with treatment or has no clear cause. It may help doctors understand why some people cough and find new ways to treat it.
Hamilton, OntarioAges 18–80 - NCT07488598Recruiting
Behavioral therapy for hard-to-treat chronic cough
This trial tests a behavioral therapy for people whose chronic cough (lasting more than 8 weeks) hasn't improved with usual treatments like asthma or reflux medicine. You may join if your cough is triggered by things like talking, laughing, cold air, or irritants, and you have throat symptoms like irritation or hoarseness.
AsyutAges 18–50 - NCT07650084RecruitingPhase 3
Testing BLU-5937 for hard-to-treat chronic cough
This 24-week study tests whether a new medicine called BLU-5937 can help adults whose chronic cough hasn't improved with standard treatments. Chronic cough that lasts a year or longer can seriously affect quality of life, and this trial explores whether this drug might provide relief.
Leshan, SichuanAges 18–80 - NCT06766175Recruiting
Cough and exercise study for chronic cough
This study looks at how chronic cough affects daily life and how a single session of intense exercise changes coughing. It may help if you have had a cough for more than 8 weeks and it bothers you a lot.
Leeds, West YorkshireAges 18 years+ - NCT06503939Enrolling by invitation
Treating long COVID cough with inhaled steroids
This trial is testing if inhaled steroid medications (ICS or ICS/LABA) can help people whose cough continues long after a COVID-19 infection. It is designed for adults whose cough started after a positive COVID test and has lasted more than 8 weeks without other lung issues.
Changsha, HunanAges 18 years+ - NCT07582549RecruitingPhase 3
Treatment for children's persistent cough
This Finnish study tests whether two common medicines (a steroid inhaler and an antibiotic) can help children whose cough has lasted more than 4 weeks without an obvious cause. Researchers want to see if these treatments work better than doing nothing.
TampereAges 1–6 - NCT05273190Recruiting
Using gentle larynx stimulation to treat chronic unexplained cough
This study tests whether stimulating the larynx (voice box area) can reduce cough that has lasted more than 8 weeks. It may help people whose cough is not clearly explained by infections, lung diseases, or other common causes.
Minneapolis, MinnesotaAges 18–88 - NCT07085975RecruitingPhase 1
Safety of inhaled ATP cough challenges
This study tests how safe and repeatable an inhaled ATP cough challenge is. It first enrolls healthy adults, then people with chronic cough or mild asthma who have not used steroid inhalers recently.
Hamilton, OntarioAges 18 years+ - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT06706765RecruitingEarly Phase 1
Cough suppression therapy via group telehealth
This study tests a behavioral therapy delivered through group video calls to help people with a chronic dry cough that has no clear cause. It may offer a non-drug way to reduce coughing.
Missoula, MontanaAges 18 years+ - NCT07232550Recruiting
Breathing study for children needing bronchoscopy
This study collects samples (like fluid from the lungs) during a planned bronchoscopy to look for new ways to understand and predict children's breathing problems. It might help if your child already needs this procedure for a medical reason.
WarsawAges Up to 17 years - NCT05086432Recruiting
Test sputum-guided care to reduce cough in lung scarring
This study uses analysis of mucus (sputum) to guide treatment with the goal of reducing long-lasting cough in adults with interstitial lung disease (ILD). You may be asked to provide sputum samples and may receive treatment decisions based on those results.
Hamilton, OntarioAges 18 years+ - NCT07671911RecruitingPhase 3
Treating IPF-related chronic cough with extended-release nalbuphine
This study tests an extended-release tablet (nalbuphine) to reduce chronic coughing in people with IPF. It may help if your cough has lasted 8 weeks or more and is bothersome.
Loxahatchee Groves, FloridaAges 40 years+ - NCT06542484Recruiting
Studying gefapixant for cough in kidney or bladder cancer
This study tests a medicine called gefapixant to see if it helps reduce chronic coughing in people with kidney or bladder cancer. You may qualify if your cough persists despite treatment and you have little to no smoking history.
Nagoya, Aichi-kenAges 18 years+
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Common questions
- Are there clinical trials for chronic cough?
- Yes. Clin2 currently lists 26 recruiting chronic cough studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic cough trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic cough trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.